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胸腔镜手术在复杂 COVID-19 患者中的应用:病例系列。

VATS in complicated COVID-19 patients: case series.

机构信息

General and Thoracic Surgery Unit, Azienda Socio Sanitaria Territoriale (ASST) Lodi, Surgical Department, Hospital of Lodi, General and Emergency Surgery, Largo Donatori del Sangue, 1, 26900, Lodi, Italy.

Emergency and Critical Care Department, Anaesthesia and Resuscitation, ASST Lodi, Lodi, Italy.

出版信息

Updates Surg. 2023 Apr;75(3):717-722. doi: 10.1007/s13304-022-01420-4. Epub 2022 Nov 16.

DOI:10.1007/s13304-022-01420-4
PMID:36385609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9668214/
Abstract

Common complications of coronavirus disease 2019 (COVID-19) related ARDS and ventilation are barotrauma-induced pneumothorax, pneumatocele and/or empyema. We analysed indications and results of video-assisted thoracoscopic surgery (VATS) in complicated COVID-19 patients. This is a retrospective single-institution study analysing a case series of patients treated by VATS for secondary spontaneous pneumothorax (SSP), pneumatocele and empyema complicating COVID-19, not responding to drainage in Lodi Maggiore Hospital between February 2020 and May 2021. Out of 2076 patients hospitalized in Lodi Maggiore Hospital with COVID-19, nine Males (0,43%; mean age 58,1-33-81) were treated by VATS for complications of pneumonia (6 SSP and 3 empyema; 1 case complicated by haemothorax). 7 patients (77%) had CPAP before surgery for 21.3 days mean (4-38). Mean Operative time was 80.9 min (38-154). Conversion rate was 0%. 3 (33%) patients were admitted to ICU before VATS. Treatments were: bullectomy in six patients (66%), drainage of the pleural space in all patients, pleural decortication and fluid aspiration in five cases (55%). two patients (22%) needed surgery interruption and bilateral ventilation to restore adequate oxygenation. Mortality was 1/9 (11%) due to respiratory failure for persistent pneumonia. In one patient (11%) redo surgery was performed for bleeding. Mean postop Length of Stay (LOS) was 37.9 days (10-77). Our report shows that VATS can be considered an extreme, but effective treatment for COVID-19 patients with SSP, pneumatocele or empyema, for patients who can tolerate general anaesthesia. Attention must be paid to the aerosol-generation of infected droplets.

摘要

2019 年冠状病毒病(COVID-19)相关急性呼吸窘迫综合征(ARDS)和通气的常见并发症是气压伤引起的气胸、肺大疱和/或脓胸。我们分析了视频辅助胸腔镜手术(VATS)治疗 COVID-19 患者复杂情况的适应证和结果。这是一项回顾性单中心研究,分析了 2020 年 2 月至 2021 年 5 月期间在洛迪马焦雷医院接受 VATS 治疗继发自发性气胸(SSP)、COVID-19 并发肺大疱和脓胸且引流无效的患者的病例系列。在洛迪马焦雷医院因 COVID-19 住院的 2076 名患者中,有 9 名男性(0.43%;平均年龄 58.1-33-81 岁)因肺炎并发症接受 VATS 治疗(6 例 SSP 和 3 例脓胸;1 例合并血胸)。7 例患者(77%)在手术前接受 CPAP 治疗 21.3 天(4-38 天)。平均手术时间为 80.9 分钟(38-154 分钟)。转化率为 0%。3 例(33%)患者在 VATS 前入住 ICU。治疗方法为:6 例患者行肺大疱切除术(66%),所有患者行胸腔引流,5 例患者行胸膜剥脱术和液体抽吸术(55%)。2 例患者(22%)需要手术中断和双侧通气以恢复足够的氧合。9 例患者中有 1 例(11%)因持续性肺炎导致呼吸衰竭而死亡。1 例患者(11%)因出血再次行手术。术后平均住院时间(LOS)为 37.9 天(10-77 天)。我们的报告表明,对于能够耐受全身麻醉的 COVID-19 患者,SSP、肺大疱或脓胸患者,VATS 可作为一种极端但有效的治疗方法。应注意感染飞沫的气溶胶生成。

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