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新冠疫情期间儿科重症监护病房作为成人重症监护场所的服务评估

The Pediatric Intensive Care Unit as a Critical Care Setting for Adults during the COVID-19 Pandemic: A Service Evaluation.

作者信息

Fitchett Elizabeth J A, Rubens Matthew, Styles Katherine, Bycroft Thomas, Nadel Simon, Gómez Carlos M H, Mitting Rebecca

机构信息

Pediatric Intensive Care Unit, Division of Women's, Children's and Clinical Support, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

University College London Great Ormond Street Institute for Child Health (UCL GOS ICH), UCL, London, United Kingdom.

出版信息

J Pediatr Intensive Care. 2021 Apr 1;11(4):335-340. doi: 10.1055/s-0041-1726454. eCollection 2022 Dec.

Abstract

One strategy to expand critical care capacity during the coronavirus disease 2019 (COVID-19) pandemic within the United Kingdom has been to repurpose other clinical departments, including the pediatric intensive care unit (PICU) and pediatric multidisciplinary team, to accommodate critically unwell adult patients. While multiple PICUs have treated adult patients with COVID-19, there is an absence of data on the characteristics of patients transferred to pediatric care and their resulting outcomes in comparison to standard adult intensive care unit (AICU) provision. Data were collected for all adult COVID-19 intensive care admissions between March and May 2020, in three ICUs within a single center: PICU, AICU, and theater recovery ICU (RICU). Patient characteristics, severity of illness, and outcomes were described according to the ICU where most of their bed-days occurred. Outcomes included duration of organ support and ICU admission, and mortality at 30 days. Mortality was compared between patients in PICU and the other adult ICUs, using a logistic regression model, adjusting for known confounding variables. Eighty-eight patients were included: 15 (17.0%) in PICU, 57 (64.7%) in AICU, and 16 (18.1%) in RICU. Patients' characteristics and illness severity on admission were comparable across locations, with similar organ support provided. Ten (66.7%) patients survived to hospital discharge from PICU, compared with 27 (47.4%) and nine (56.3%) patients from AICU and RICU, respectively, with no significant difference in 30-day mortality (OR 0.46, 95% CI 0.12-1.85;  = 0.276). Our analysis illustrates the feasibility of evaluating outcomes of patients who have been cared for in additional, emergency ICU beds, whilst demonstrating comparable outcomes for adults cared for in pediatric and adult units.

摘要

在英国2019年冠状病毒病(COVID-19)大流行期间,扩大重症监护能力的一项策略是重新利用其他临床科室,包括儿科重症监护病房(PICU)和儿科多学科团队,以收治病情严重的成年患者。虽然多个PICU都收治了COVID-19成年患者,但与标准的成人重症监护病房(AICU)相比,目前缺乏转至儿科治疗的患者特征及其治疗结果的数据。收集了2020年3月至5月期间,在一个中心的三个重症监护病房(PICU、AICU和手术室恢复重症监护病房[RICU])中,所有成年COVID-19重症监护入院患者的数据。根据患者大部分住院日所在的重症监护病房,描述患者特征、疾病严重程度和治疗结果。治疗结果包括器官支持和重症监护病房住院时间,以及30天死亡率。使用逻辑回归模型,对已知的混杂变量进行调整,比较PICU患者与其他成人重症监护病房患者的死亡率。共纳入88例患者:15例(17.0%)在PICU,57例(64.7%)在AICU,16例(18.1%)在RICU。各地点患者入院时的特征和疾病严重程度相当,提供的器官支持也相似。PICU有10例(66.7%)患者存活至出院,AICU和RICU分别为27例(47.4%)和9例(56.3%),30天死亡率无显著差异(比值比0.46,95%置信区间0.12 - 1.85;P = 0.276)。我们的分析说明了评估在额外的急诊重症监护病房床位接受治疗的患者治疗结果的可行性,同时表明在儿科和成人病房接受治疗的成人患者治疗结果相当。

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