青光眼与眼表疾病：不止于所见
Glaucoma and Ocular Surface Disease: More than Meets the Eye.
作者信息
Li Gavin, Akpek Esen Karamursel, Ahmad Sumayya
机构信息
Department of Ophthalmology at the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ocular Surface Disease Clinic, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Clin Ophthalmol. 2022 Nov 4;16:3641-3649. doi: 10.2147/OPTH.S388886. eCollection 2022.
Understanding the association between ocular surface disease and glaucoma is important for improving adherence to treatment and introducing practical solutions. While topical antihypertensive medications for glaucoma are well tolerated according to short-term studies, there is little evidence on their long-term effects. Since they are often required for many years, the effects of these drops on the ocular surface become important in regard to quality of life and adherence. In this nonsystematic review performed in April 2022, we summarize what is known about the relationship between glaucoma and ocular surface disease. Specifically, we examine how each class of topical glaucoma drops affects the ocular surface. We then review the treatment of ocular surface disease for patients on topical glaucoma therapy. Finally, we discuss treatments that may reduce or eliminate the burden of topical medications.
了解眼表疾病与青光眼之间的关联对于提高治疗依从性和引入切实可行的解决方案至关重要。虽然根据短期研究，用于治疗青光眼的局部抗高血压药物耐受性良好，但关于其长期影响的证据却很少。由于这些药物通常需要使用多年，因此这些滴眼液对眼表的影响在生活质量和依从性方面变得至关重要。在2022年4月进行的这项非系统性综述中，我们总结了关于青光眼与眼表疾病之间关系的已知信息。具体而言，我们研究了每一类局部青光眼滴眼液如何影响眼表。然后，我们回顾了接受局部青光眼治疗的患者眼表疾病的治疗方法。最后，我们讨论了可能减轻或消除局部用药负担的治疗方法。
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