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关于新冠病毒疫苗接种后的月经变化和子宫异常出血

Apropos of menstrual changes and abnormal uterine bleeding after COVID-19 vaccination.

作者信息

Roncati Luca, Manenti Antonio

机构信息

Department of Surgery, Medicine, Dentistry and Morphological Sciences with interest in Transplantation, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

出版信息

Brain Hemorrhages. 2022 Nov 8. doi: 10.1016/j.hest.2022.11.001.

DOI:10.1016/j.hest.2022.11.001
PMID:36406341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9642033/
Abstract

It is news of 28 October 2022 that the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency has recommended to add heavy menstrual bleeding among the side effects of unknown frequency inside the package insert of nucleoside-modified messenger ribonucleic acid vaccines to prevent coronavirus disease 2019 (COVID-19). The decision has been made in the light of the numerous reports of unexpected menstrual changes or abnormal uterine bleeding following COVID-19 vaccination. Here we advance a possible involvement of the particular adenohypophyseal microcirculation in these strange and still unexplained events.

摘要

2022年10月28日有消息称,欧洲药品管理局药物警戒风险评估委员会建议在预防2019冠状病毒病(COVID-19)的核苷修饰信使核糖核酸疫苗的药品说明书中,将月经过多列为频率不明的副作用之一。该决定是鉴于有大量报告称接种COVID-19疫苗后出现意外月经变化或子宫异常出血。在此,我们提出腺垂体特殊微循环可能与这些奇怪且仍无法解释的事件有关。

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本文引用的文献

1
Discovery of a trans-sellar vascular supply for the pituitary gland.垂体跨鞍区血管供应的发现。
Anat Cell Biol. 2022 Jun 30;55(2):124-129. doi: 10.5115/acb.21.255. Epub 2022 May 23.
2
Pituitary apoplexy following adenoviral vector-based COVID-19 vaccination.基于腺病毒载体的新冠疫苗接种后垂体卒中
Brain Hemorrhages. 2023 Mar;4(1):27-29. doi: 10.1016/j.hest.2022.04.002. Epub 2022 Apr 19.
3
A Three-Case Series of Thrombotic Deaths in Patients over 50 with Comorbidities Temporally after modRNA COVID-19 Vaccination.
50岁以上合并症患者在接受mRNA新冠疫苗接种后短期内发生血栓形成死亡的三例系列病例
Pathogens. 2022 Apr 3;11(4):435. doi: 10.3390/pathogens11040435.
4
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J Thromb Thrombolysis. 2021 Nov;52(4):1043-1046. doi: 10.1007/s11239-021-02444-0. Epub 2021 Apr 12.
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Nucleoside-modified messenger RNA COVID-19 vaccine platform.核苷修饰的信使 RNA COVID-19 疫苗平台。
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