一名外科医生因针刺伤继发原发性耐多药结核病：一个被忽视的问题。
Primary Multidrug-resistant Tuberculosis in a Surgeon Secondary to a Needlestick Injury: A Neglected Problem.
作者信息
Yang Meifang, Xu Min, Zhang Xuan, Zhao Hong, Hu Jianhua, Wang Jie
机构信息
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People's Republic of China.
Research Units of Infectious Disease and Microecology, Chinese Academy of Medical Sciences, Hangzhou, Zhejiang Province, People's Republic of China.
出版信息
Infect Drug Resist. 2022 Nov 14;15:6651-6657. doi: 10.2147/IDR.S387363. eCollection 2022.
Healthcare workers (HCWs) are highly at risk for tuberculosis (TB) exposure, particularly those in high TB burden countries. Inoculation TB secondary to needlestick injury is uncommon but can occur in HCWs. Herein, we report an unusual case of primary multidrug-resistant tuberculosis (MDR-TB) in a surgeon secondary to a needlestick injury while performing thoracentesis on a TB patient, and the surgeon recovered and returned to work after 22 months of anti-TB treatment. We searched the PubMed database and identified 19 cases of inoculation TB secondary to sharp injury in HCWs including the present case. Those cases highlight that primary inoculation of TB even MDR-TB infection should not be neglected in patients suffered needlestick injury when the sharp instrument suspected or confirmed contaminated with TB. In this situation, if the HCWs need for additional protection or prophylactic anti-TB is worthy of further study.
医护人员（HCWs）面临着很高的结核病（TB）暴露风险，尤其是在结核病负担较重国家的医护人员。针刺伤继发的接种性结核病并不常见，但在医护人员中可能发生。在此，我们报告一例不寻常的病例，一名外科医生在为一名结核病患者进行胸腔穿刺术时因针刺伤继发原发性耐多药结核病（MDR-TB），该外科医生在接受22个月的抗结核治疗后康复并重返工作岗位。我们检索了PubMed数据库，确定了包括本病例在内的19例医护人员锐器伤继发接种性结核病的病例。这些病例表明，当锐器疑似或确诊被结核杆菌污染时，对于针刺伤患者，即使是原发性接种性耐多药结核病感染也不应被忽视。在这种情况下，医护人员是否需要额外的保护或预防性抗结核治疗值得进一步研究。
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