Division of Endocrinology, Diabetes and Metabolism, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.
Endocrinology, Diabetes and Nutrition, Médical Center EndoDia-Centre, Biel-Bienne, Switzerland.
Front Endocrinol (Lausanne). 2022 Nov 3;13:1041232. doi: 10.3389/fendo.2022.1041232. eCollection 2022.
Iodine is essential for the biosynthesis of thyroid hormones, which are crucial for intrauterine growth and fetal neurocognitive development. Iodine requirements increase during pregnancy and lactation. The World Health Organization and the Swiss Confederation recommend a total daily iodine intake of 250 µg of iodine during preconception, pregnancy and lactation. To assure this goal, several professional organizations recommend complementing the nutritional iodine intake with supplements containing 150 μg of iodine daily.
Prenatal and adult multivitamins widely available in Switzerland were compiled to determine their iodine content. Obstetricians verified that the list includes the most frequently prescribed supplements in Switzerland.
A total of 44 adult multivitamin supplements were identified, 23 of which are specifically intended for women planning pregnancy, pregnant, or breastfeeding. Seven out of 23 (30.4%) prenatal multivitamins products, and 12/21 (57.1%) adult multivitamins contained no iodine. Among all the products, only 18/44 (40.9%) contain 150 µg of iodine or more.
Several widely used products contain no or insufficient amounts (<150 ug) of iodine. Providers need to be informed about the variability in iodine content of supplements and established recommendations, and manufacturers of prenatal supplements should assure that their products contain iodine in adequate amounts.
碘是甲状腺激素合成所必需的，甲状腺激素对宫内生长和胎儿神经认知发育至关重要。怀孕期间和哺乳期对碘的需求增加。世界卫生组织和瑞士联邦建议在受孕前、怀孕和哺乳期每天摄入总碘 250µg。为了确保这一目标，一些专业组织建议用每天补充 150µg 碘的补充剂来补充营养碘的摄入。
编译了瑞士广泛使用的产前和成人多种维生素，以确定其碘含量。妇产科医生证实，该清单包括瑞士最常开的补充剂。
共确定了 44 种成人多种维生素补充剂，其中 23 种专门针对计划怀孕、怀孕或哺乳期的妇女。23 种产前多种维生素产品中有 7 种（30.4%），21 种成人多种维生素中有 12 种（57.1%）不含碘。在所有产品中，只有 18/44（40.9%）种含有 150µg 或更多的碘。
几种广泛使用的产品不含碘或含量不足（<150ug）。需要向提供者通报补充剂中碘含量的可变性和既定建议，产前补充剂的制造商应确保其产品含有足够量的碘。
