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孕前、孕期及哺乳期女性的碘补充:美国产科医生和助产士的当前临床实践

Iodine Supplementation in Women During Preconception, Pregnancy, and Lactation: Current Clinical Practice by U.S. Obstetricians and Midwives.

作者信息

De Leo Simone, Pearce Elizabeth N, Braverman Lewis E

机构信息

1 Endocrine Unit, Fondazione IRCCS Cà Granda , Milan, Italy .

2 Department of Clinical Sciences and Community Health, University of Milan , Milan, Italy .

出版信息

Thyroid. 2017 Mar;27(3):434-439. doi: 10.1089/thy.2016.0227. Epub 2016 Dec 22.

Abstract

BACKGROUND

Iodine deficiency is a major public-health problem throughout the world, especially for pregnant women, and it is considered the most common cause of preventable intellectual impairment. In the United States, iodine status in pregnant women is considered mildly deficient. Therefore, the Endocrine Society, the American Thyroid Association, the Teratology Society, and the American Academy of Pediatrics recommend that women receive prenatal vitamins containing 150 μg of iodine daily during preconception, pregnancy, and lactation. The objectives of this study were to evaluate awareness of iodine nutrition among obstetricians and midwives in the United States, and to document current clinical practice regarding recommendations for iodine supplementation for women during preconception, pregnancy, and lactation.

METHODS

All midwife members of the American College of Nurse-Midwives (ACNM) and all obstetrician members of the American Medical Association (AMA) were invited to participate in a web-based survey.

RESULTS

A total of 199 midwives and 277 obstetricians participated in the survey. One third of both obstetricians and midwives considered iodine status in U.S. pregnant women to be deficient. Although almost all obstetricians and midwives would recommend prenatal multivitamins, most reported rarely or never recommending iodine-containing multivitamins for women planning pregnancy (68.7% and 70.2%, respectively), pregnant women (66% and 67.1%), or lactating women (68.7% and 71.7%). Of the respondents who did report prescribing iodine-containing supplements, 85% recommended supplementation during the first trimester and 75-80% during the second and third trimesters. However, of those who did recommend iodine supplementation, only 45% would prescribe the recommended 150 μg of iodine daily during pregnancy. Overall, 75% of U.S. obstetricians and midwives do not recommend or would recommend an inadequate amount of iodine during preconception, pregnancy, and lactation.

CONCLUSIONS

Despite the important consequences of iodine deficiency for pregnant women and the recommendations of many medical societies, the majority of U.S. obstetricians and midwives who participated in this survey do not recommend iodine-containing vitamins in women planning pregnancy, during pregnancy, and during lactation.

摘要

背景

碘缺乏是全球主要的公共卫生问题,对孕妇而言尤为如此,并且它被认为是可预防的智力损害的最常见原因。在美国,孕妇的碘状况被认为轻度缺乏。因此,美国内分泌学会、美国甲状腺协会、致畸学学会以及美国儿科学会建议女性在孕前、孕期和哺乳期每日摄入含150微克碘的产前维生素。本研究的目的是评估美国产科医生和助产士对碘营养的知晓情况,并记录当前关于孕前、孕期和哺乳期女性碘补充建议的临床实践。

方法

邀请美国护士助产士学院(ACNM)的所有助产士成员以及美国医学协会(AMA)的所有产科医生成员参与一项基于网络的调查。

结果

共有199名助产士和277名产科医生参与了调查。产科医生和助产士中有三分之一认为美国孕妇的碘状况不足。尽管几乎所有产科医生和助产士都会推荐产前多种维生素,但大多数人报告说很少或从不为计划怀孕的女性(分别为68.7%和70.2%)、孕妇(66%和67.1%)或哺乳期女性(68.7%和71.7%)推荐含碘多种维生素。在确实报告开具含碘补充剂的受访者中,85%建议在孕早期补充,75% - 80%建议在孕中期和孕晚期补充。然而,在那些确实建议补充碘的人中,只有45%会在孕期每日开具推荐的150微克碘。总体而言,75%的美国产科医生和助产士在孕前、孕期和哺乳期不推荐或会推荐不足量的碘。

结论

尽管碘缺乏对孕妇有重要影响且有许多医学学会给出了建议,但参与本次调查的大多数美国产科医生和助产士在计划怀孕的女性、孕期女性和哺乳期女性中不推荐含碘维生素。

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