在一家三级护理大学医院的肝病 ICU 住院的肝硬化和非肝硬化患者的预后和预后标志物。
Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital.
机构信息
Endemic Medicine and Hepatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
National Research Institute, Cairo, Egypt.
出版信息
Afr Health Sci. 2022 Jun;22(2):377-383. doi: 10.4314/ahs.v22i2.43.
BACKGROUND AND AIM
Patients with decompensated liver cirrhosis are not given priority for ICU admission in the settings of limited place availability. Recently, advances in medical care led to improvement in their survival. Our aim is to study the outcome of patients admitted to our hepatology ICU.
METHODS
We retrieved the data of patients admitted to the Endemic Medicine Department ICU at Kasr Al-Ainy Hospital in the period from November 2014 to May 2018. We included 498 patients who had complete clinical and outcome data in this analysis. The primary outcome was ICU mortality and its predictors.
RESULTS
The overall mortality was 48.1% in the liver cirrhosis versus 52.9% in the non-cirrhosis group. The most common presentations of cirrhotic patients were hepatic encephalopathy and hypovolemic shock. The SOFA score and sepsis independently predicted mortality in the overall cohort.
CONCLUSION
The mortality of cirrhotic patients admitted to ICU is not higher than non-cirrhotic patients. SOFA score is a good prognostic indicator in patients with cirrhosis.
背景与目的
在 ICU 床位有限的情况下，失代偿期肝硬化患者通常不会优先获得 ICU 入院治疗的机会。然而，近年来医疗技术的进步使他们的存活率得到了提高。本研究旨在探讨入住我院传染病科 ICU 的肝硬化患者的预后。
方法
我们检索了 2014 年 11 月至 2018 年 5 月期间入住 Kasr Al-Ainy 医院传染病科 ICU 的患者数据。对所有纳入患者的临床资料及预后进行了分析，共纳入 498 例患者，所有患者均有完整的临床及预后资料。主要转归为 ICU 死亡率及其预测因素。
结果
肝硬化患者 ICU 死亡率为 48.1%，非肝硬化患者为 52.9%。肝硬化患者最常见的表现为肝性脑病和低血容量性休克。SOFA 评分和脓毒症是全队列患者死亡的独立预测因素。
结论
入住 ICU 的肝硬化患者死亡率并不高于非肝硬化患者。SOFA 评分是肝硬化患者的良好预后指标。
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