O'Sullivan Brian, Burton Tom, Ziad Fouzia, Meyer Rochow Goswin
Department of General Surgery, Waikato Hospital, Hamilton, New Zealand.
Department of Pathology, Waikato Hospital, Hamilton, New Zealand.
Clin Pathol. 2022 Nov 14;15:2632010X221134569. doi: 10.1177/2632010X221134569. eCollection 2022 Jan-Dec.
Papillary Thyroid cancer (PTC) is the most common malignancy encountered by endocrine surgeons accounting for up to 85% to 90% of all thyroid malignancies. Parathyroid metastases appear to be an uncommon phenomenon however are likely to be underdiagnosed due to routine parathyroid gland preservation during thyroidectomy.
We present the case of 63-year-old lady with PTC metastases to the parathyroid gland. She underwent total thyroidectomy, central compartment lymph node dissection and selective left neck (levels IIA-IV) lymph node dissection. Final pathology confirmed a 45 mm low grade conventional type papillary carcinoma with microscopic extension into perithyroidal soft tissue focally and into the adjacent left parathyroid gland.
Parathyroid gland thyroid cancer infiltration/metastasis is rarely reported and likely underdiagnosed. This is the first case of parathyroid gland metastasis reported from New Zealand or Australia to our knowledge. There is currently limited research available to guide whether parathyroid gland infiltration or metastasis is of clinical or prognostic significance and whether a more aggressive treatment strategy is warranted when present.
甲状腺乳头状癌（PTC）是内分泌外科医生最常遇到的恶性肿瘤，占所有甲状腺恶性肿瘤的85%至90%。甲状旁腺转移似乎是一种罕见现象，但由于甲状腺切除术中常规保留甲状旁腺，可能存在诊断不足的情况。
我们报告了一例63岁女性发生甲状旁腺转移的甲状腺乳头状癌病例。她接受了全甲状腺切除术、中央区淋巴结清扫术和选择性左侧颈部（IIA-IV区）淋巴结清扫术。最终病理证实为45毫米低级别传统型乳头状癌，显微镜下可见局部侵犯甲状腺周围软组织并累及相邻左侧甲状旁腺。
甲状旁腺受甲状腺癌浸润/转移的报道很少，可能存在诊断不足的情况。据我们所知，这是新西兰或澳大利亚报道的首例甲状旁腺转移病例。目前，关于甲状旁腺浸润或转移是否具有临床或预后意义，以及出现这种情况时是否需要更积极的治疗策略，可供参考的研究有限。
