Oliaee Anahita, Mohebbi Maryam, Shirani Sepehr, Rostami Reza
Department of Biomedical Engineering, Faculty of Electrical Engineering, K.N. Toosi University of Technology, Tehran, Iran.
Department of Psychology, Faculty of Psychology, University of Tehran, Tehran, Iran.
Cogn Neurodyn. 2022 Dec;16(6):1249-1259. doi: 10.1007/s11571-022-09794-2. Epub 2022 Mar 7.
Dyslexia is a neurological disorder manifested as difficulty reading and writing. It can occur despite adequate instruction, intelligence, and intact sensory abilities. Different electroencephalogram (EEG) patterns have been demonstrated between dyslexic and healthy subjects in previous studies. This study focuses on the difference between patients before and after treatment. The main goal is to identify the subset of features that adequately discriminate subjects before and after a specific treatment plan. The treatment consists of Transcranial Direct Current Stimulation (tDCS) and occupational therapy using the BrainWare SAFARI software. The EEG signals of sixteen dyslexic children were recorded during the eyes-closed resting state before and after treatment. The preprocessing step was followed by the extraction of a wide range of features to investigate the differences related to the treatment. An optimal subset of features extracted from recorded EEG signals was determined using Principal Component Analysis (PCA) in conjunction with the Sequential Floating Forward Selection (SFFS) algorithm. The results showed that treatment leads to significant changes in EEG features like spectral and phase-related EEG features, in various regions. It has been demonstrated that the extracted subset of discriminative features can be useful for classification applications in treatment assessment. The most discriminative subset of features could classify the data with an accuracy of 92% with SVM classifier. The above result confirms the efficacy of the treatment plans in improving dyslexic children's cognitive skills.
阅读障碍是一种神经障碍,表现为阅读和书写困难。尽管接受了充分的指导、具备一定智力且感觉能力完好,仍可能出现这种情况。先前的研究表明,阅读障碍患者与健康受试者之间存在不同的脑电图(EEG)模式。本研究聚焦于治疗前后患者的差异。主要目标是确定能够充分区分特定治疗方案前后受试者的特征子集。治疗包括经颅直流电刺激(tDCS)和使用BrainWare SAFARI软件的职业治疗。在治疗前后的闭眼静息状态下,记录了16名阅读障碍儿童的EEG信号。在预处理步骤之后,提取了广泛的特征以研究与治疗相关的差异。使用主成分分析(PCA)结合顺序浮动前向选择(SFFS)算法,确定了从记录的EEG信号中提取的特征的最优子集。结果表明,治疗会导致EEG特征在各个区域出现显著变化,如与频谱和相位相关的EEG特征。已经证明,提取的判别特征子集可用于治疗评估中的分类应用。最具判别力的特征子集使用支持向量机(SVM)分类器对数据进行分类的准确率可达92%。上述结果证实了治疗方案在提高阅读障碍儿童认知技能方面的有效性。