Engstrom Teyl, Tanner Sarah, Lee Wen Ray, Forbes Cheryl, Walker Rick, Bradford Natalie, Pole Jason D
Centre for Health Services Research, The University of Queensland, Herston, QLD, Australia.
School of Medicine, The University of Queensland, Herston, QLD, Australia; Queensland Children's Hospital, Brisbane, QLD, Australia; Princess Alexandra Hospital, Brisbane, QLD, Australia.
Crit Rev Oncol Hematol. 2023 Jan;181:103867. doi: 10.1016/j.critrevonc.2022.103867. Epub 2022 Nov 22.
Adolescent and young adult (AYA) cancer patients and survivors are growing and face with distinct issues from paediatric and older cancer survivors. Hence it is important the issues they encounter are measured using appropriate Patient Reported Outcome Measures (PROMs). We searched PubMed, EMBASE, CINAHL, and PsycINFO for articles including: (1) AYAs (ages 15-39), (2) Malignant neoplasms, and (3) PROMs. This resulted in 3566 unique articles, 523 were included for full text review, of which 175 were included. These studies included 203 distinct tools to measure PROMs across 31 domains. Physical function was most frequently measured domain, followed by social, emotional and mental health. The most commonly used tools were the EORTC QLQ-C30, HADS and SF-36. PROMs used in AYA cancer patients is a complex topic, this comprehensive review serves as a useful reference for researchers, clinicians and health services who want to better understand, and improve, outcomes among their patients.
青少年和青年（AYA）癌症患者及幸存者群体正在不断壮大，他们面临着与儿童癌症幸存者和老年癌症幸存者不同的问题。因此，使用适当的患者报告结局测量指标（PROMs）来衡量他们所遇到的问题非常重要。我们在PubMed、EMBASE、CINAHL和PsycINFO中搜索了包含以下内容的文章：（1）青少年和青年（年龄在15 - 39岁之间），（2）恶性肿瘤，以及（3）患者报告结局测量指标。这产生了3566篇独特的文章，其中523篇被纳入全文审查，最终175篇被纳入。这些研究包括203种用于测量31个领域患者报告结局测量指标的不同工具。身体功能是最常被测量的领域，其次是社会、情感和心理健康。最常用的工具是欧洲癌症研究与治疗组织核心问卷（EORTC QLQ - C30）、医院焦虑抑郁量表（HADS）和健康调查简表（SF - 36）。青少年和青年癌症患者使用的患者报告结局测量指标是一个复杂的主题，这篇全面的综述为希望更好地了解并改善其患者结局的研究人员、临床医生和卫生服务人员提供了有用的参考。
