Department of Chemistry, University of South Africa, Florida Campus, Cnr Christiaan de Wet Rd & Pioneer Avenue, Florida Park, Roodepoort 1709, South Africa.
Institute for Nanotechnology and Water Sustainability, College of Science Engineering and Technology, University of South Africa, Corner Christiaan de Wet and Pioneer Avenue, Florida Park, Roodepoort 1709, South Africa.
Int J Environ Res Public Health. 2022 Nov 13;19(22):14922. doi: 10.3390/ijerph192214922.
Pollutants mainly exist as multicomponent mixtures in the environment. Therefore, it is necessary to synthesize low-cost adsorbents that can simultaneously adsorb multiple compounds. This work presents the prospect of the adsorption of multiclass pharmaceuticals from the aqueous environment using an adsorbent derived from silk fibroin of the wild silkworm . The adsorbent was prepared by dissolving degummed silk fibroin and the resultant solution was cast to obtain films that were ball-milled to powder. FTIR results revealed bands corresponding to N-H and C=O stretching vibrations. Particle size distribution data generally showed two size groups in the range of 50-90 nm and 250-625 nm. The study focused on the adsorptive removal of multiple compounds consisting of eight pharmaceuticals representing various classes including a β-blocker (pindolol), anesthetic (lidocaine), stimulant (caffeine), antiviral (nevirapine), steroid (estriol), anti-epileptic (carbamazepine), and a non-steroidal anti-inflammatory drug (naproxen). The adsorption process was best fitted to the pseudo-second-order isotherm and an overall match to the Freundlich model. Thermodynamic parameters suggested that the process was mainly exothermic and more spontaneous at lower temperatures. The performance of the adsorbent was further evaluated using environmental waters and the adsorbent demonstrated good potential for simultaneous adsorption of multicomponent pharmaceuticals.
污染物在环境中主要以多组分混合物的形式存在。因此，有必要合成能够同时吸附多种化合物的低成本吸附剂。本工作提出了利用野蚕丝素蛋白制备吸附剂从水环境中吸附多类药物的前景。该吸附剂通过溶解脱胶丝素蛋白并将所得溶液浇铸得到薄膜，然后将薄膜球磨成粉末。傅里叶变换红外光谱（FTIR）结果显示出对应于 N-H 和 C=O 伸缩振动的谱带。粒度分布数据通常显示出两个尺寸组，范围在 50-90nm 和 250-625nm 之间。该研究集中于吸附去除由八种药物组成的多种化合物，这些药物代表了各种类别，包括β受体阻滞剂（pindolol）、麻醉剂（利多卡因）、兴奋剂（咖啡因）、抗病毒药（奈韦拉平）、甾体（雌三醇）、抗癫痫药（卡马西平）和非甾体抗炎药（萘普生）。吸附过程最符合准二级等温线，总体上符合 Freundlich 模型。热力学参数表明，该过程主要是放热的，在较低温度下更自发。进一步使用环境水样评估了吸附剂的性能，结果表明该吸附剂具有同时吸附多种药物的良好潜力。
