Department of Organic and Inorganic Chemistry, Faculty of Sciences, University of Extremadura, Avda de Elvas, s/n E-06071 Badajoz, Spain.
J Hazard Mater. 2010 May 15;177(1-3):1046-53. doi: 10.1016/j.jhazmat.2010.01.026. Epub 2010 Jan 13.
The adsorption of two non-steroidal anti-inflammatory drugs (NSAIDs), namely naproxen and ketoprofen, has been studied. Low-cost carbonaceous materials such as carbon blacks have been used as the adsorbents. The influence of temperature (20-60 degrees C), pH (3-11), ionic strength (0.01-0.1M), textural properties of the adsorbents (S(BET) and pore volumes) and aqueous matrix on the adsorption process has been analyzed. The adsorption isotherms have been determined both in milli-Q aqueous solution and water from the Guadiana river. Ionic strength and pH exert a noticeable influence on the process. In general, the removal is favored at low values of temperature and pH. On the contrary, an increase of the ionic strength seems to favor the adsorption process. The use of more porous adsorbents results in a more effective removal of the pollutants. Finally, the use of natural river water results in a noticeable increase of the removal capacity of naproxen and, particularly, ketoprofen. The experimental results proved that, under the optimal operation conditions, up to 517mg/g of naproxen and 400mg/g of ketoprofen may be adsorbed, which demonstrates the promising potential of these adsorbents for the removal of the pharmaceuticals under study.
本文研究了两种非甾体抗炎药（NSAIDs），即萘普生和酮洛芬的吸附情况。使用了廉价的碳质材料（如炭黑）作为吸附剂。分析了温度（20-60℃）、pH 值（3-11）、离子强度（0.01-0.1M）、吸附剂的结构性质（BET 比表面积和孔体积）和水基质对吸附过程的影响。在 Milli-Q 水溶液和瓜迪亚纳河水中测定了吸附等温线。离子强度和 pH 值对该过程有明显影响。一般来说，低温和低 pH 值有利于去除。相反，增加离子强度似乎有利于吸附过程。使用更具多孔性的吸附剂可更有效地去除污染物。最后，使用天然河水会显著增加萘普生和酮洛芬的去除能力。实验结果表明，在最佳操作条件下，可吸附高达 517mg/g 的萘普生和 400mg/g 的酮洛芬，这证明了这些吸附剂在去除研究中这些药物方面具有广阔的应用前景。
