基于 3,4-二羟基苯甲酸配体的铜金属有机骨架的吸附容量、抑制活性及加工技术。
Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand.
机构信息
Departamento de Química Aplicada, Facultad de Química, Universidad del País Vasco UPV/EHU, Paseo Manuel Lardizabal, N° 3, 20018 Donostia-San Sebastián, Spain.
Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, Spain.
出版信息
Molecules. 2022 Nov 21;27(22):8073. doi: 10.3390/molecules27228073.
Due to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF-namely -that displays the formula [CuL(DMF)] (DMF = ,-dimethylformamide) is described, synthesized by the combination of copper(II) and 3,4-dihydroxybenzoic acid (HL)-both having well-known antibacterial properties. The resulting three-dimensional structure motivated us to study the antibacterial activity, adsorptive capacity and processability of the MOF in the form of pellets and membranes as a proof-of-concept to evaluate its future application in devices.
由于抗生素耐药菌的快速出现和发展，寻找新的、有效的方法来对抗这些病原体至关重要；在这种情况下，金属有机骨架（MOFs）是有效对抗它们的有前途的材料。在此，描述了一种新型的 Cu-MOF，即 [CuL(DMF)]（DMF = 二甲基甲酰胺），它是通过铜（II）和 3,4-二羟基苯甲酸（HL）的组合合成的，两者都具有众所周知的抗菌性能。所得的三维结构促使我们研究该 MOF 的抗菌活性、吸附能力和以颗粒和膜形式的加工性能，作为概念验证来评估其在设备中的未来应用。
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