Department of Surgery, Faculty of Medicine, Jouf University, Saudi Arabia; Department of Surgery, Faculty of Medicine for Girls, Al-Azhar University, Egypt.
Department of Surgery, Faculty of Medicine for Girls, Al-Azhar University, Egypt.
Asian J Surg. 2023 Aug;46(8):3017-3026. doi: 10.1016/j.asjsur.2022.11.002. Epub 2022 Nov 11.
Several studies have proven that COVID-19 is linked to a higher incidence of different thrombotic events. Thrombosis of the portal vein can result in portal hypertension and can extend to the mesenteric vein resulting in intestinal ischemia. A search of PubMed, Web of Science, and Scopus for relevant studies revealed an association between PVT and COVID-19. This review is structured according to PRISMA guidelines. Thirty-three studies met the inclusion criteria. Twenty-nine case studies/series and four cohort/cross-sectional studies were included. Age at diagnosis was lower when compared to PVT due to cirrhosis. In cohort/cross-sectional studies, males comprised 54.83% of subjects, whereas in case reports/series, males comprised 62.1%. Obesity, asthma, hypertension, and diabetes were the most common comorbidities identified. The majority of the thrombotic events occurred within two weeks. The treatment aimed to prevent thrombus progression and improve recanalization. According to the evidence, early intervention prevents the poor prognosis of intestinal ischemia and its propagation.
多项研究证实，COVID-19 与不同血栓事件的发生率增加有关。门静脉血栓形成可导致门静脉高压，并延伸至肠系膜静脉导致肠缺血。在 PubMed、Web of Science 和 Scopus 中搜索相关研究，发现 PVT 与 COVID-19 之间存在关联。本综述根据 PRISMA 指南进行构建。符合纳入标准的研究有 33 项。纳入了 29 项病例研究/系列和 4 项队列/横断面研究。与因肝硬化导致的 PVT 相比，诊断时的年龄更低。在队列/横断面研究中，男性占 54.83%，而在病例报告/系列中，男性占 62.1%。肥胖、哮喘、高血压和糖尿病是最常见的合并症。大多数血栓形成事件发生在两周内。治疗旨在预防血栓进展和改善再通。根据证据，早期干预可预防肠缺血及其传播的不良预后。
