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生物学和医学在量子优势的领域中。

Biology and medicine in the landscape of quantum advantages.

机构信息

Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR 97202, USA.

Intel Labs, Santa Clara, CA 95054, USA.

出版信息

J R Soc Interface. 2022 Nov;19(196):20220541. doi: 10.1098/rsif.2022.0541. Epub 2022 Nov 30.

Abstract

Quantum computing holds substantial potential for applications in biology and medicine, spanning from the simulation of biomolecules to machine learning methods for subtyping cancers on the basis of clinical features. This potential is encapsulated by the concept of a quantum advantage, which is contingent on a reduction in the consumption of a computational resource, such as time, space or data. Here, we distill the concept of a quantum advantage into a simple framework to aid researchers in biology and medicine pursuing the development of quantum applications. We then apply this framework to a wide variety of computational problems relevant to these domains in an effort to (i) assess the potential of practical advantages in specific application areas and (ii) identify gaps that may be addressed with novel quantum approaches. In doing so, we provide an extensive survey of the intersection of biology and medicine with the current landscape of quantum algorithms and their potential advantages. While we endeavour to identify specific computational problems that may admit practical advantages throughout this work, the rapid pace of change in the fields of quantum computing, classical algorithms and biological research implies that this intersection will remain highly dynamic for the foreseeable future.

摘要

量子计算在生物学和医学中有广泛的应用潜力,涵盖了从生物分子模拟到基于临床特征对癌症进行亚型分类的机器学习方法。这种潜力可以用量子优势的概念来概括,而量子优势取决于计算资源(如时间、空间或数据)消耗的减少。在这里,我们将量子优势的概念提炼成一个简单的框架,以帮助生物学和医学领域的研究人员开发量子应用。然后,我们将该框架应用于与这些领域相关的各种计算问题,以评估在特定应用领域中实际优势的潜力,并确定可能需要新的量子方法来解决的差距。通过这样做,我们广泛调查了生物学和医学与当前量子算法及其潜在优势的交叉领域。虽然我们努力在整个工作中确定可能具有实际优势的具体计算问题,但量子计算、经典算法和生物研究领域的快速变化意味着,在可预见的未来,这一交叉领域仍将具有高度动态性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45e7/9709576/3b5321318425/rsif20220541f01.jpg

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