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生物信息学中的量子计算:系统综述图谱

Quantum computing in bioinformatics: a systematic review mapping.

机构信息

Artificial Intelligence Division, Institute of Computer Science, Faculty of Electronics and Information Technology, Warsaw University of Technology, Nowowiejska 15/19, 00-665 Warsaw, Poland.

Independent Researcher, Warsaw, Poland.

出版信息

Brief Bioinform. 2024 Jul 25;25(5). doi: 10.1093/bib/bbae391.

DOI:10.1093/bib/bbae391
PMID:39140856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11323091/
Abstract

The field of quantum computing (QC) is expanding, with efforts being made to apply it to areas previously covered by classical algorithms and methods. Bioinformatics is one such domain that is developing in terms of QC. This article offers a broad mapping review of methods and algorithms of QC in bioinformatics, marking the first of its kind. It presents an overview of the domain and aids researchers in identifying further research directions in the early stages of this field of knowledge. The work presented here shows the current state-of-the-art solutions, focuses on general future directions, and highlights the limitations of current methods. The gathered data includes a comprehensive list of identified methods along with descriptions, classifications, and elaborations of their advantages and disadvantages. Results are presented not just in a descriptive table but also in an aggregated and visual format.

摘要

量子计算(QC)领域正在不断扩展,人们正在努力将其应用于传统算法和方法所涵盖的领域。生物信息学就是这样一个在 QC 方面发展的领域。本文对生物信息学中的 QC 方法和算法进行了广泛的映射综述,这在该领域尚属首次。它概述了该领域,并帮助研究人员在该领域的早期阶段确定进一步的研究方向。这里展示的工作展示了当前的最新解决方案,重点关注一般的未来方向,并突出了当前方法的局限性。收集的数据包括已识别方法的综合列表,以及对其优缺点的描述、分类和详细说明。结果不仅以描述性表格呈现,还以聚合和可视化格式呈现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/9358ccc7915d/bbae391f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/f769f36bc926/bbae391f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/9b79d5393e76/bbae391f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/1d0badb92507/bbae391f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/9358ccc7915d/bbae391f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/f769f36bc926/bbae391f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/9b79d5393e76/bbae391f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/1d0badb92507/bbae391f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/633b/11323091/9358ccc7915d/bbae391f4.jpg

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本文引用的文献

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Brief Bioinform. 2024 Jan 22;25(2). doi: 10.1093/bib/bbae074.
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Quantum Computing and the Future of Neurodegeneration and Mental Health Research.量子计算与神经退行性疾病及心理健康研究的未来
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Single-Molecule Identification of Nucleotides Using a Quantum Computer.
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J Phys Chem B. 2023 Aug 3;127(30):6636-6642. doi: 10.1021/acs.jpcb.3c02918. Epub 2023 Jul 19.
4
Quantum computing on nucleic acid research: Approaching towards next-generation computing.量子计算在核酸研究中的应用:迈向新一代计算
Mol Ther Nucleic Acids. 2023 Jun 28;33:53-56. doi: 10.1016/j.omtn.2023.06.007. eCollection 2023 Sep 12.
5
Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics.量子计算在下一代计算生物学领域的应用:从蛋白质折叠到分子动力学。
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6
Quantum Computing for Molecular Biology.量子计算在分子生物学中的应用。
Chembiochem. 2023 Jul 3;24(13):e202300120. doi: 10.1002/cbic.202300120. Epub 2023 Jun 1.
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Data on the solution and processing time reached when constructing a phylogenetic tree using a quantum-inspired computer.关于使用量子启发式计算机构建系统发育树时所达到的解决方案和处理时间的数据。
Data Brief. 2023 Feb 13;47:108970. doi: 10.1016/j.dib.2023.108970. eCollection 2023 Apr.
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