从 中分离得到具有 α-葡萄糖苷酶抑制活性的新齐墩果烷型三萜皂苷。
A new oleanane-type triterpenoid saponin with α-glucosidase inhibitory activity from .
机构信息
College of Pharmacy, Guilin Medical University, Guilin 541199, China.
College of Biotechnology, Guilin Medical University, Guilin 541199, China.
出版信息
J Asian Nat Prod Res. 2023 Sep;25(9):890-898. doi: 10.1080/10286020.2022.2152012. Epub 2022 Nov 30.
A new oleanane-type triterpenoid saponin, 21, 22-di--angeloyl-15, 16, 28-trihydroxyolean-12-ene 3---L-rhamnopyranosyl-(1→3)--D-xylopyranosyl-(1→3)--D-glucopyranoside (), together with five known compounds (), were isolated from . Their structures were elucidated based on spectroscopic methods, including extensive NMR and MS spectra. Compound showed potential inhibitory activity on α-glucosidase with the IC values of 185.9 ± 44.5 µmol/L.
一种新的齐墩果烷型三萜皂苷，21,22-二--当归酰基-15,16,28-三羟基齐墩-12-烯 3---L-鼠李吡喃糖基-(1→3)--D-木吡喃糖基-(1→3)--D-吡喃葡萄糖苷 ()，与五种已知化合物 ()一起从 中分离得到。它们的结构是基于光谱方法，包括广泛的 NMR 和 MS 光谱来阐明的。化合物 对 α-葡萄糖苷酶表现出潜在的抑制活性，IC 值为 185.9 ± 44.5 μmol/L。
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