Tabesh Elham, Ghassami Maryam, Rezayatmand Reza, Tahmasebi Marzieh, Adibi Payman
Isfahan Gastroenterology and Hepatology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Gastroenterologist, Isfahan University of Medical Sciences, Isfahan, Iran.
Int J Prev Med. 2022 Oct 11;13:135. doi: 10.4103/ijpvm.ijpvm_714_20. eCollection 2022.
Colorectal cancer (CRC) is the third most common cancer among adults in Iran. The aim of colorectal cancer screening is to reduce the cancer burden in the population by diagnosing the disease in its early stages.
We adapted this guideline for the moderate CRC risk population for Isfahan to determine how to screen them and when to start and end the CRC screening. This guideline was developed by clinical appraisal and review of the evidence, available clinical guidelines, and in consultation with members of the Isfahan Chamber of Iranian association of gastroenterology and hepatology.
In screening people with average risk for CRC who use personal resources and personally pay all the costs, colonoscopy is recommended as the first choice to be done every 10 years. In case of negative colonoscopy, we recommend FIT test to prevention of interval cancer every 5 years. In screening of people with average risk of CRC, FIT is suggested to be done every 2 years as a first-choice method test for those who use public resources and do not pay for this service personally. In screening individuals with average risk for CRC, g-FOBT is not recommended as the first method of choice. Repeating positive guaiac test is not recommended and if positive, colonoscopy is suggested.
结直肠癌（CRC）是伊朗成年人中第三大常见癌症。结直肠癌筛查的目的是通过在疾病早期进行诊断来减轻人群中的癌症负担。
我们针对伊斯法罕中度结直肠癌风险人群调整了本指南，以确定如何对他们进行筛查以及何时开始和结束结直肠癌筛查。本指南是通过对证据、现有临床指南进行临床评估和审查，并与伊朗胃肠病学和肝病学协会伊斯法罕分会成员协商制定的。
在筛查使用个人资源并自行承担所有费用的结直肠癌平均风险人群时，建议每10年进行一次结肠镜检查作为首选。如果结肠镜检查结果为阴性，我们建议每5年进行一次粪便免疫化学试验（FIT）以预防间期癌。在筛查结直肠癌平均风险人群时，对于使用公共资源且不自行支付此项服务费用的人群，建议每2年进行一次FIT作为首选方法检测。在筛查结直肠癌平均风险个体时，不建议将愈创木脂粪便隐血试验（g-FOBT）作为首选方法。不建议重复进行阳性愈创木脂试验，如果结果为阳性，则建议进行结肠镜检查。
