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[绵羊鼻窦腺癌:摩洛哥首例病例描述]

[Adenocarcinoma of the paranasal sinuses in sheep: First case description in Morocco].

作者信息

Zouagui Z, Ait Lbacha H, Khoumiri A, Kichou F

机构信息

Unité de pathologie médicale et chirurgicale des ruminants, Institut Agronomique et Vétérinaire Hassan II, Madinat Al Irfane, Rabat, Maroc.

Unité d'expertise, ANMV - ANSES, Fougères, France .

出版信息

Schweiz Arch Tierheilkd. 2022 Dec;164(12):861-868. doi: 10.17236/sat00379.

Abstract

Small ruminant sinus adenocarcinoma (ENA) is a contagious disease caused by a beta retrovirus called Enzootic Nasal Tumor Virus or ENTV. The first cases were sporadically diagnosed in Morocco in 2018. However, in the last two years, ENTV has appeared enzootic in three herds of the Sardi breed. The annual incidence varied between 5 and 20 %. Most cases involved female animals aged 15 to 42 months. The disease developed within 2 to a maximum of 6 months. Diseased animals presented with progressive weight loss and increased mortality or needed to be slaughtered. The condition associated mainly with unilateral skull deformation, serous or seromucous nasal discharge with dyspnea, and in some individuals an exophthalmos. During pathology tumor-like masses were found in the paranasal sinuses, which showed the growth of an expansive and organized epithelial neoplasm on histopathology. After an overview of the differential diagnoses that can lead to confusion with ANE, the authors investigate why the disease occurs more frequently in Morocco and particularly in the Sardi breed.

摘要

小型反刍动物鼻窦腺癌(ENA)是一种由称为地方性鼻肿瘤病毒(ENTV)的β逆转录病毒引起的传染病。2018年在摩洛哥首次偶发诊断出该病。然而,在过去两年中,ENTV在三个撒丁岛品种的畜群中呈地方流行。年发病率在5%至20%之间。大多数病例涉及15至42个月大的雌性动物。该病在2至最多6个月内发展。患病动物出现渐进性体重减轻和死亡率增加,或需要被屠宰。该病主要与单侧颅骨变形、伴有呼吸困难的浆液性或浆液黏液性鼻分泌物有关,在一些个体中还伴有眼球突出。在病理学检查中,在鼻窦中发现了肿瘤样肿块,组织病理学显示为一种膨胀性和有组织的上皮性肿瘤生长。在概述了可能与ANE混淆的鉴别诊断后,作者研究了为什么该病在摩洛哥,特别是在撒丁岛品种中更频繁发生。

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