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Leptin-loaded Extracellular Vesicles Treat Sleep-disordered Breathing in Mice with Obesity.

作者信息

Freire Carla, Ramsey Jacob D, Pho Huy, Kojima Ryo, Zhao Yuling, Kim Lenise, Anokye-Danso Frederick, Berger Slava, Ahima Rexford S, Batrakova Elena V, Kabanov Alexander V, Polotsky Vsevolod Y

机构信息

The Johns Hopkins School of Medicine Baltimore, Maryland.

University of North Carolina at Chapel Hill Chapel Hill, North Carolina.

出版信息

Am J Respir Cell Mol Biol. 2022 Dec;67(6):720-723. doi: 10.1165/rcmb.2022-0229LE.

DOI:10.1165/rcmb.2022-0229LE
PMID:36454084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9743189/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3b/9743189/3b24c7b397e5/rcmb.2022-0229LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3b/9743189/3b24c7b397e5/rcmb.2022-0229LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3b/9743189/3b24c7b397e5/rcmb.2022-0229LEf1.jpg

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Nat Nanotechnol. 2021 Jul;16(7):748-759. doi: 10.1038/s41565-021-00931-2. Epub 2021 Jul 1.
2
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Am J Respir Cell Mol Biol. 2020 Oct;63(4):502-509. doi: 10.1165/rcmb.2020-0117OC.
3
Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.
瘦素通过作用于颈动脉体中的瞬时受体电位 M 通道诱导高血压。
Circ Res. 2019 Nov 8;125(11):989-1002. doi: 10.1161/CIRCRESAHA.119.315338. Epub 2019 Sep 23.
4
TPP1 Delivery to Lysosomes with Extracellular Vesicles and their Enhanced Brain Distribution in the Animal Model of Batten Disease.TPP1 通过细胞外囊泡递送至溶酶体及其在神经鞘脂贮积症动物模型中的脑内分布增强。
Adv Healthc Mater. 2019 Jun;8(11):e1801271. doi: 10.1002/adhm.201801271. Epub 2019 Apr 18.
5
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6
Sleep-disordered breathing in C57BL/6J mice with diet-induced obesity.饮食诱导肥胖 C57BL/6J 小鼠的睡眠呼吸紊乱。
Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy089.
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Oxid Med Cell Longev. 2018 Feb 20;2018:5137947. doi: 10.1155/2018/5137947. eCollection 2018.
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