Department of Ophthalmology, Gui de Chauliac Hospital, Montpellier, France.
Montpellier Centre Ophtalmologie, Montpellier, France.
Ophthalmic Res. 2023;66(1):474-480. doi: 10.1159/000526281. Epub 2022 Dec 5.
The aims of this study were to study ocular biometric data and their association with age and sex in a population of cataract surgery candidates and to assess the proportion of inhomogeneous eyes and the ratio anterior segment (AS) to axial length (AL). Multicentric cross-sectional analysis was conducted between April 2008 and May 2021 in public and private ophthalmic institutions in Montpellier, France. Individuals ≥40 years old who underwent ocular biometry before cataract surgery were included.
Right phakic eyes were included. Ocular biometrics were measured by using the Lenstar LS900 device. We defined AS as anterior chamber depth (ACD) plus lens thickness (LT) and calculated the ratio of AS to AL. We defined inhomogeneous eyes as those with deep AS (≥4th quartile) and short AL (≤1st quartile) (AS+) or with short AS and high AL (AL+).
We included 11,650 individuals (11,650 eyes) (mean [SD] age 71.64 [10.50] years; 54.51% women). Older age was associated with shorter AL (p < 0.01), shallower ACD (p < 0.01), thinner central corneal thickness (p < 0.01), and larger LT (p < 0.001). Women had shorter AL, shallower ACD, and thinner central corneal thickness than men (p < 0.001). In total, 778 (6.68%) eyes were inhomogeneous (3.22% AS+ and 3.46% AL+), for a mean (SD) AS/AL ratio of 0.36 (0.01) and 0.28 (0.01), respectively, as compared with 0.32 (0.02) for homogeneous eyes (p < 0.001).
The AS/AL ratio could be useful to screen inhomogeneous eyes before cataract surgery and justify the use of new generation formulas in these eyes to avoid the risk of refractive error.
本研究旨在研究白内障手术候选人群的眼部生物测量数据及其与年龄和性别的关系，并评估不均匀眼的比例和前节（AS）与眼轴（AL）的比值。2008 年 4 月至 2021 年 5 月，在法国蒙彼利埃的公立和私立眼科机构进行了多中心横断面分析。纳入年龄≥40 岁并在白内障手术前接受眼部生物测量的患者。
纳入右眼正视眼。使用 Lenstar LS900 设备测量眼部生物测量值。我们将 AS 定义为前房深度（ACD）加晶状体厚度（LT），并计算 AS 与 AL 的比值。我们将深 AS（≥第 4 四分位数）和短 AL（≤第 1 四分位数）（AS+）或短 AS 和高 AL（AL+）的眼睛定义为不均匀眼。
共纳入 11650 名个体（11650 只眼）（平均[标准差]年龄 71.64[10.50]岁；54.51%为女性）。年龄较大与较短的 AL（p < 0.01）、较浅的 ACD（p < 0.01）、较薄的中央角膜厚度（p < 0.01）和较大的 LT（p < 0.001）相关。女性的 AL、ACD 较浅和中央角膜厚度较薄，均短于男性（p < 0.001）。总共有 778 只（6.68%）眼不均匀（3.22% AS+和 3.46% AL+），平均（标准差）AS/AL 比值分别为 0.36（0.01）和 0.28（0.01），而均匀眼的比值为 0.32（0.02）（p < 0.001）。
AS/AL 比值可用于白内障术前筛选不均匀眼，并证明在这些眼中使用新一代公式以避免屈光误差的风险是合理的。
