Department of Ophthalmology, the First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, 215006, China.
BMC Ophthalmol. 2020 Dec 7;20(1):481. doi: 10.1186/s12886-020-01754-w.
The purpose of this study was to investigate the agreement of lens thickness (LT) measurements made by contact A-scan ultrasonography and Lenstar LS900 as well as the influence of anterior chamber depth (ACD) and axial length (AL) measurement differences on LT measurement in cataract patients in the two techniques.
1247 cataract patients (1247 eyes) participated in this retrospective cross-sectional study. Ocular biometric measurements were performed with Lenstar LS900 and A-scan ultrasonography respectively, and the measured results of AL, ACD and LT were compared using Pearson correlation coefficients (r) and Bland-Altman analyses.
Bland-Altman analyses showed poor agreement between the A-scan ultrasonography and Lenstar LS900 in measuring AL and ACD. The average difference of LT was 0.01 mm; the consistency limit was - 0.86 mm, 0.88 mm; and 95.27% of datapoints were within the 95% consistency limit. The consistency of LT measurements between the two techniques was poor for those subjects whose ACD or AL values were beyond the 95% consistency limit. Among the subjects whose AL or ACD values measured by A-scan ultrasonography were greater than those measured by Lenstar LS900, 93.33% of them were within the 95% consistency limit, suggesting that the consistency of LT measurement between the two techniques was poor. Of patients whose ACD or AL measured by A-scan ultrasonography were smaller than that of Lenstar LS900, 96.01% of them were within the 95% consistency limit.
There was good agreement of the LT measurements between A-scan ultrasonography and Lenstar LS900, except for the axis deviating from the apparent axis during A-scan ultrasonography. If this error can be avoided, A-scan ultrasonography can replace Lenstar LS900 in LT measurement in cataract patients.
本研究旨在探讨接触式 A 超超声与 Lenstar LS900 测量晶状体厚度（LT）的一致性，以及前房深度（ACD）和眼轴长度（AL）测量值差异对两种技术中白内障患者 LT 测量值的影响。
本回顾性横断面研究纳入了 1247 例（1247 只眼）白内障患者。分别使用 Lenstar LS900 和 A 超进行眼生物测量，采用 Pearson 相关系数（r）和 Bland-Altman 分析比较 AL、ACD 和 LT 的测量结果。
Bland-Altman 分析显示，A 超与 Lenstar LS900 在测量 AL 和 ACD 方面一致性较差。LT 的平均差值为 0.01mm；一致性限为-0.86mm，0.88mm；95.27%的数据点在 95%一致性限内。对于 ACD 或 AL 值超出 95%一致性限的患者，两种技术测量 LT 的一致性较差。在 A 超测量的 AL 或 ACD 值大于 Lenstar LS900 测量值的患者中，93.33%的患者在 95%一致性限内，提示两种技术测量 LT 的一致性较差。在 A 超测量的 ACD 或 AL 值小于 Lenstar LS900 的患者中，96.01%的患者在 95%一致性限内。
A 超与 Lenstar LS900 测量 LT 的一致性较好，但 A 超测量时眼球轴位与实际轴位偏离时除外。如果能避免这种误差，A 超可在白内障患者 LT 测量中替代 Lenstar LS900。
