Soleimani Anahita, Keivani Nadia, Lotfipour Samane, Abolhasani Sakhavat, Valizadeh Soghra, Behniafar Hamed
Student Research Committee, Sarab Faculty of Medical Sciences, Sarab, East Azerbaijan Iran.
Department of Clinical Biochemestry, Sarab Faculty of Medical Sciences, Sarab, East Azerbaijan Iran.
J Parasit Dis. 2022 Dec;46(4):1192-1203. doi: 10.1007/s12639-022-01532-z. Epub 2022 Sep 21.
Strongyloidiasis could be a significant global health issue undervalued in several countries, which is caused by spp. Challenges stemming from the use of anthelmintic chemotherapy, such as the development of resistance, the progressive cost of medicines, environmental toxicity of chemicals, and residuals in beast products have increased interest in promoting alternative means of control for the use of plant-based parasite control methods. A study on herbal extracts may offer a less expensive yet equally effective alternative for the prevention and treatment of helminthic multi-resistance. We systematically searched the Web of Sciences, PubMed/MEDLINE, and Scopus databases to explore original publications related to medicinal plants and in English on September 29, 2021. The keywords of medicinal plant, traditional medicine, plant extract, herbal medicine, herbal extract, natural drug, , strongyloidiasis, infection, and helminth were used in our search. Researchers can make use of this review as a quick reference. In this study, we have summarized recent advancements and published investigations on herbal and naturally derived medicines in treating strongyloidiasis undertaken by several researchers worldwide. These medicinal herbs, as well as the active and significant compounds they contain, such as alkaloids, phenolic derivatives, tannins, and terpenes, have been outlined in recent articles. Various studies on herbal remedies to treat strongyloidiasis have been undertaken to date, but further research is still required on moderately effective and low harmful substances.
粪类圆线虫病可能是一个在多个国家被低估的重大全球健康问题,它由粪类圆线虫属物种引起。使用驱虫化疗带来的挑战,如耐药性的产生、药品成本的不断增加、化学物质对环境的毒性以及畜产品中的残留,使得人们对推广基于植物的寄生虫控制方法等替代控制手段的兴趣增加。一项关于草药提取物的研究可能为预防和治疗蠕虫多重耐药性提供一种成本较低但同样有效的替代方法。我们于2021年9月29日系统地搜索了科学网、PubMed/MEDLINE和Scopus数据库,以探索与药用植物和粪类圆线虫病相关的英文原始出版物。我们在搜索中使用了药用植物、传统医学、植物提取物、草药、草药提取物、天然药物、粪类圆线虫病、感染和蠕虫等关键词。研究人员可以将本综述作为快速参考。在本研究中,我们总结了世界各地一些研究人员在治疗粪类圆线虫病方面对草药和天然衍生药物的最新进展和已发表的研究。这些药草以及它们所含的活性和重要化合物,如生物碱、酚类衍生物、单宁和萜类,已在最近的文章中进行了概述。迄今为止,已经开展了各种关于治疗粪类圆线虫病草药疗法的研究,但对于中等有效性和低有害物质仍需要进一步研究。