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印度猴痘的产科护理:每位临床医生都应了解的内容。

Obstetric Care for Monkey Pox in India: What Every Clinician Should Know.

作者信息

Balsarkar Geetha

机构信息

Seth G.S. Medical College and Nowrosjee Wadia Maternity Hospital, Mumbai, India.

出版信息

J Obstet Gynaecol India. 2022 Oct;72(5):373-376. doi: 10.1007/s13224-022-01717-9. Epub 2022 Oct 8.

Abstract

Monkeypox is a contagious viral disease that spreads between animals and people. The UK government guidance described the first case of 'Monkey Pox' in 1958, when it was found only in monkeys used for research purposes. Fortunately, for a third world fast developing country like India, monkeypox does not spread easily in the population but spread by close physical contact between people, and there is limited information available about the impact on pregnancy. The virus can enter the body through broken skin, the respiratory tract, or mucous membranes (the moist inner lining of cavities and some organs in the body). The signs and symptoms of monkeypox virus infection in people who are pregnant appear similar to those in nonpregnant people. The symptoms include fever, lymphadenopathy, lethargy, pharyngitis, headache, myalgias, and rash. Rash associated with monkeypox virus infection can be found in the anogenital area (most commonly reported location in this current outbreak), trunk, arms, legs, face, and the palms and soles. The diagnostic approach to a patient with suspected monkeypox virus infection is the same for pregnant and nonpregnant people. If a patient is present with signs and symptoms of monkeypox virus infection, diagnostic testing should be considered, especially if the person has risk factors for monkeypox virus infection. There are limited data on monkeypox infection during pregnancy. It is unknown whether pregnant people are more susceptible to monkeypox virus or whether infection is more severe in pregnancy. Monkeypox virus can be transmitted to the fetus during pregnancy or to the newborn by close contact during and after birth. Adverse pregnancy outcomes, including spontaneous pregnancy loss and stillbirth, have been reported in cases of confirmed monkeypox infection during pregnancy. Preterm delivery and neonatal monkeypox infection have also been reported. Monkeypox virus can be transmitted to the fetus during pregnancy or to the newborn by close contact during and after birth. Adverse pregnancy outcomes, including spontaneous pregnancy loss and stillbirth, have been reported in cases of confirmed monkeypox infection during pregnancy. Infection control practices for the care of patients who are pregnant with monkeypox infection are the same as those for patients who are not pregnant with monkeypox infection. This includes appropriate isolation of patients with monkeypox; training for health-care personnel on maternity and newborn care units on correct adherence to infection control practices and personal protective equipment (PPE) use and handling; and ensuring sufficient and appropriate PPE supplies are positioned at all points of care. Furthermore, visitors to pregnant or postpartum patients with monkeypox should be strictly limited to those essential for the patient's care and well-being, and should have no direct contact with the patient. Use of alternative mechanisms for patient and visitor interactions, such as video-call applications, should be encouraged for any additional support. CDC also recommends pregnant, postnatal, and breastfeeding women should be prioritized for medical treatment as there is a significant risk to the baby. They also identify these groups as eligible for treatment.

摘要

猴痘是一种在动物与人之间传播的传染性病毒性疾病。英国政府指南描述了1958年的首例“猴痘”病例,当时仅在用于研究目的的猴子身上发现。幸运的是,对于像印度这样的第三世界快速发展国家来说,猴痘在人群中不易传播,但通过人与人之间的密切身体接触传播,而且关于其对妊娠影响的可用信息有限。该病毒可通过破损皮肤、呼吸道或黏膜(身体腔隙和一些器官的湿润内衬)进入人体。孕妇感染猴痘病毒的体征和症状与非孕妇相似。症状包括发热、淋巴结病、嗜睡、咽炎、头痛、肌痛和皮疹。与猴痘病毒感染相关的皮疹可出现在肛门生殖器区域(本次疫情中最常报告的部位)、躯干、手臂、腿部、面部以及手掌和脚底。对疑似猴痘病毒感染患者的诊断方法,孕妇和非孕妇相同。如果患者出现猴痘病毒感染的体征和症状,应考虑进行诊断检测,尤其是如果该人有猴痘病毒感染的危险因素。关于孕期猴痘感染的数据有限。尚不清楚孕妇是否更容易感染猴痘病毒,或者感染在孕期是否更严重。猴痘病毒可在孕期传播给胎儿,或在出生期间及出生后通过密切接触传播给新生儿。在确诊孕期猴痘感染的病例中,已报告了不良妊娠结局,包括自然流产和死产。也有早产和新生儿猴痘感染的报告。猴痘病毒可在孕期传播给胎儿,或在出生期间及出生后通过密切接触传播给新生儿。在确诊孕期猴痘感染的病例中,已报告了不良妊娠结局,包括自然流产和死产。对感染猴痘的孕妇的感染控制措施与未感染猴痘的孕妇相同。这包括对猴痘患者进行适当隔离;对产科和新生儿护理单位的医护人员进行培训,使其正确遵守感染控制措施以及个人防护装备(PPE)的使用和处理;并确保在所有护理点都有充足且合适的PPE供应。此外,猴痘感染孕妇或产后患者的访客应严格限于对患者护理和福祉至关重要的人员,且不应与患者有直接接触。对于任何额外支持,应鼓励使用视频通话应用等患者与访客互动的替代机制。美国疾病控制与预防中心还建议,由于对婴儿有重大风险,应优先为孕妇、产后妇女和哺乳期妇女提供医疗治疗。他们还确定这些人群符合治疗条件。

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