• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

未分化多形性肉瘤致心脏压塞:病例报告及文献复习。

Undifferentiated Pleomorphic Sarcoma Presenting With Cardiac Tamponade: A Case Report and Review.

机构信息

Texas Tech University Health Sciences Center El Paso, USA.

出版信息

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221141190. doi: 10.1177/23247096221141190.

DOI:10.1177/23247096221141190
PMID:36458807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9720795/
Abstract

Soft tissue sarcomas (STS) comprise a large group of heterogeneous malignant tumors that form approximately 1% of all adult malignancies. Most sarcomas originate from soft tissue and the rest arise from the bone. Undifferentiated pleomorphic sarcoma (UPS) is an aggressive tumor that usually presents as an asymptomatic subcutaneous mass that exhibits rapid growth with unremarkable skin findings. The diagnosis is usually made with histopathology or immunohistochemistry; once the diagnosis is confirmed, evaluation and workup of the primary tumor, lymph nodes, and metastasis should be made. Treatment is stage-dependent but generally involves en-bloc resection followed by a review of pathology with a discussion of the benefits of adjuvant radiation or chemotherapy. Here, we discuss a case of a 77-year-old patient who presented with a large mass over the right shoulder and echocardiographic findings of cardiac tamponade.

摘要

软组织肉瘤(STS)是一组异质性恶性肿瘤,约占所有成人恶性肿瘤的 1%。大多数肉瘤起源于软组织,其余则来自骨骼。未分化多形性肉瘤(UPS)是一种侵袭性肿瘤,通常表现为无症状的皮下肿块,生长迅速,皮肤表现无明显特征。诊断通常通过组织病理学或免疫组织化学进行;一旦确诊,应评估和检查原发性肿瘤、淋巴结和转移灶。治疗取决于分期,但通常包括整块切除,然后对病理进行审查,并讨论辅助放疗或化疗的益处。在这里,我们讨论了一个 77 岁患者的病例,该患者右侧肩部出现一个大肿块,并伴有心脏压塞的超声心动图表现。

相似文献

1
Undifferentiated Pleomorphic Sarcoma Presenting With Cardiac Tamponade: A Case Report and Review.未分化多形性肉瘤致心脏压塞:病例报告及文献复习。
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221141190. doi: 10.1177/23247096221141190.
2
Cardiac Tamponade as an Unusual Initial Clinical Manifestation of CIC-DUX4 Sarcoma.心脏压塞为 CIC-DUX4 肉瘤的一种不常见初始临床表现。
Am J Case Rep. 2021 Feb 28;22:e929349. doi: 10.12659/AJCR.929349.
3
Primary cardiac undifferentiated sarcoma of the right atrium presenting with cardiac tamponade.以心脏压塞为表现的右心房原发性心脏未分化肉瘤。
Cardiovasc Pathol. 2009 Mar-Apr;18(2):110-3. doi: 10.1016/j.carpath.2007.10.006. Epub 2007 Dec 3.
4
An unusual case of metastasis of a pulmonary undifferentiated pleomorphic sarcoma to the right ventricle: a case report.一例罕见的肺未分化多形性肉瘤转移至右心室的病例报告
J Med Case Rep. 2013 Jun 27;7:165. doi: 10.1186/1752-1947-7-165.
5
Pericardial sarcoma.心包肉瘤
BMJ Case Rep. 2018 Oct 7;2018:bcr-2018-226112. doi: 10.1136/bcr-2018-226112.
6
Undifferentiated and dedifferentiated soft tissue neoplasms: Immunohistochemical surrogates for differential diagnosis.未分化和去分化软组织肿瘤:用于鉴别诊断的免疫组织化学替代物。
Semin Diagn Pathol. 2021 Nov;38(6):170-186. doi: 10.1053/j.semdp.2021.09.005. Epub 2021 Sep 29.
7
Eleven cases of cardiac metastases from soft-tissue sarcomas.软组织肉瘤心脏转移 11 例。
Jpn J Clin Oncol. 2011 Apr;41(4):514-8. doi: 10.1093/jjco/hyq246. Epub 2011 Jan 19.
8
Gigantic undifferentiated pleomorphic sarcoma (UPS) of breast in a woman: A rare case report.一名女性乳腺巨大未分化多形性肉瘤(UPS):罕见病例报告。
Int J Surg Case Rep. 2023 Aug;109:108605. doi: 10.1016/j.ijscr.2023.108605. Epub 2023 Aug 2.
9
Use of Ultrasound for Evaluation of a Large Undifferentiated Pleomorphic Sarcoma in the Lower Extremity of an Elderly Male.超声在评估一名老年男性下肢大型未分化多形性肉瘤中的应用
Cureus. 2022 Oct 10;14(10):e30153. doi: 10.7759/cureus.30153. eCollection 2022 Oct.
10
Primary pleomorphic breast sarcoma - a case report.原发性多形性乳腺肉瘤——1 例报告。
Folia Med (Plovdiv). 2024 Aug 31;66(4):568-573. doi: 10.3897/folmed.66.e120391.

引用本文的文献

1
Surgical resection of a rare biatrial giant sarcoma: a case report.罕见双房巨大肉瘤的手术切除:一例报告
J Cardiothorac Surg. 2025 Apr 11;20(1):186. doi: 10.1186/s13019-025-03439-1.
2
Cardiac Tumors Causing Sudden Cardiac Death: A State-of-the-Art Review in Pathology.导致心源性猝死的心脏肿瘤:病理学的最新综述
Cancers (Basel). 2025 Feb 17;17(4):669. doi: 10.3390/cancers17040669.
3
Among the Masses: Multiple Left Atrial Undifferentiated Pleomorphic Sarcomas.群体中:多发左房未分化多形性肉瘤

本文引用的文献

1
The clinical utility of next-generation sequencing for bone and soft tissue sarcoma.下一代测序在骨和软组织肉瘤中的临床应用。
Acta Oncol. 2022 Jan;61(1):38-44. doi: 10.1080/0284186X.2021.1992009. Epub 2021 Oct 22.
2
Mediastinal undifferentiated pleomorphic sarcoma with pleural effusion cytopathologically misdiagnosed as epithelial malignant pleural mesothelioma: An autopsy case report.纵隔未分化多形性肉瘤伴胸腔积液,细胞病理学误诊为上皮性恶性胸膜间皮瘤:尸检病例报告。
Thorac Cancer. 2021 Apr;12(7):1137-1140. doi: 10.1111/1759-7714.13898. Epub 2021 Feb 19.
3
The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives.
Ochsner J. 2024 Winter;24(4):279-283. doi: 10.31486/toj.23.0143.
2020 年世界卫生组织软组织肿瘤分类:新闻与展望。
Pathologica. 2021 Apr;113(2):70-84. doi: 10.32074/1591-951X-213. Epub 2020 Nov 3.
4
Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab.SARC028 试验的相关性分析显示肉瘤相关免疫浸润与帕博利珠单抗应答之间存在关联。
Clin Cancer Res. 2020 Mar 15;26(6):1258-1266. doi: 10.1158/1078-0432.CCR-19-1824. Epub 2020 Jan 3.
5
Undifferentiated Pleomorphic Sarcoma: Long-Term Follow-Up from a Large Institution.未分化多形性肉瘤:来自大型机构的长期随访
Cancer Manag Res. 2019 Nov 27;11:10001-10009. doi: 10.2147/CMAR.S226896. eCollection 2019.
6
Predicting the prognosis of undifferentiated pleomorphic soft tissue sarcoma: a 20-year experience of 266 cases.未分化多形性软组织肉瘤的预后预测:266例患者的20年经验
ANZ J Surg. 2019 Sep;89(9):1045-1050. doi: 10.1111/ans.15348. Epub 2019 Jul 30.
7
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.拉罗替尼在成人和儿童TRK融合阳性癌症中的疗效。
N Engl J Med. 2018 Feb 22;378(8):731-739. doi: 10.1056/NEJMoa1714448.
8
Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.帕博利珠单抗治疗晚期软组织肉瘤和骨肉瘤(SARC028):一项多中心、双队列、单臂、开放标签的2期试验。
Lancet Oncol. 2017 Nov;18(11):1493-1501. doi: 10.1016/S1470-2045(17)30624-1. Epub 2017 Oct 4.
9
Clinical effect of molecular methods in sarcoma diagnosis (GENSARC): a prospective, multicentre, observational study.肉瘤诊断中分子方法的临床效果(GENSARC):一项前瞻性、多中心、观察性研究。
Lancet Oncol. 2016 Apr;17(4):532-538. doi: 10.1016/S1470-2045(15)00583-5. Epub 2016 Mar 10.
10
Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone.肉瘤分类:基于 2013 年世界卫生组织软组织和骨肿瘤分类的更新。
Cancer. 2014 Jun 15;120(12):1763-74. doi: 10.1002/cncr.28657. Epub 2014 Mar 19.