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罕见双房巨大肉瘤的手术切除:一例报告

Surgical resection of a rare biatrial giant sarcoma: a case report.

作者信息

Wu Jingyi, Lin Yimei, Liu Juanlan, Wu Junmei, Zhang Hao, Liang Chao

机构信息

Department of Anesthesiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.

Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, China.

出版信息

J Cardiothorac Surg. 2025 Apr 11;20(1):186. doi: 10.1186/s13019-025-03439-1.

DOI:10.1186/s13019-025-03439-1
PMID:40217257
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11987167/
Abstract

Primary cardiac undifferentiated sarcoma is an exceptionally rare entity, marked by nonspecific symptoms that considerably challenge its diagnosis and treatment. Surgical resection generally serves as the primary treatment modality. This article describes the case of a 32-year-old female patient admitted to the hospital with symptoms of abdominal distension and pain. Subsequent echocardiography revealed a cardiac tumor that occupied almost the entire left and right atria. The tumor was surgically removed in an emergency procedure, and subsequent pathological examination confirmed an undifferentiated sarcoma. The patient was successfully discharged 17 days after surgery. She then completed six cycles of chemotherapy. A six-month follow-up showed no signs of tumor recurrence or metastasis.

摘要

原发性心脏未分化肉瘤是一种极为罕见的疾病,其症状不具有特异性,这给诊断和治疗带来了极大挑战。手术切除通常是主要的治疗方式。本文描述了一名32岁女性患者的病例,该患者因腹胀和腹痛症状入院。随后的超声心动图检查发现一个几乎占据整个左右心房的心脏肿瘤。该肿瘤在急诊手术中被切除,随后的病理检查证实为未分化肉瘤。患者术后17天成功出院。之后她完成了六个周期的化疗。六个月的随访显示没有肿瘤复发或转移的迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/51d9b49dc1b1/13019_2025_3439_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/86bde8d94e4e/13019_2025_3439_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/bbec40a7cf8f/13019_2025_3439_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/51d9b49dc1b1/13019_2025_3439_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/86bde8d94e4e/13019_2025_3439_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/bbec40a7cf8f/13019_2025_3439_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05c/11987167/51d9b49dc1b1/13019_2025_3439_Fig3_HTML.jpg

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本文引用的文献

1
Undifferentiated Pleomorphic Sarcoma Presenting With Cardiac Tamponade: A Case Report and Review.未分化多形性肉瘤致心脏压塞:病例报告及文献复习。
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221141190. doi: 10.1177/23247096221141190.
2
A Rare Case of Undifferentiated Pleomorphic Cardiac Sarcoma with Inflammatory Pattern.一种罕见的具有炎症模式的未分化多形性心脏肉瘤。
Medicina (Kaunas). 2022 Jul 28;58(8):1009. doi: 10.3390/medicina58081009.
3
Primary cardiac undifferentiated pleomorphic sarcoma is associated with TP53 mutation during lack of MDM2 amplification, and targeted sequencing analysis reveals potentially actionable targets.
原发性心脏未分化多形性肉瘤与MDM2未扩增时的TP53突变相关,靶向测序分析揭示了潜在的可操作靶点。
Hum Pathol. 2022 May;123:113-122. doi: 10.1016/j.humpath.2022.02.006. Epub 2022 Feb 15.
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The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities.《2020 年世卫组织软组织肿瘤分类:精选变更和新实体》。
Adv Anat Pathol. 2021 Jan;28(1):44-58. doi: 10.1097/PAP.0000000000000284.
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Primary cardiac dedifferentiated liposarcoma in a middle-aged female: a case report.中年女性原发性心脏去分化脂肪肉瘤:一例报告
J Cardiothorac Surg. 2019 Aug 30;14(1):156. doi: 10.1186/s13019-019-0973-0.
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[Cardiac tumors].[心脏肿瘤]
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