Department of Midwifery, College of Medicine and Health Science, Wolaita Sodo University, Sodo, Ethiopia.
Department of Reproductive Health, College of Medicine and Health Science, Wolaita Sodo University, Sodo, Ethiopia.
Hum Vaccin Immunother. 2022 Dec 30;18(7):2145821. doi: 10.1080/21645515.2022.2145821. Epub 2022 Dec 2.
Immunization is cost-effective preventive strategy for child morbidity and mortality. PubMed, Google Scholar, Scopus, Science Direct, and online institutional repository homes were searched. Data were extracted by Microsoft excel. Begg's rank test, and Egger's regression test was done. A pooled prevalence, Sub-group analysis, sensitivity analysis and meta-regression were conducted. A total of 12 articles were included in this study. The pooled prevalence of vaccination dropout was 26.06% (95% CI: 11.59, 30.53), I2 =91.2%. In sub-group analysis, Nigeria had the highest prevalence of immunization dropouts (33.59%). It was 18.01% and 29.25%, respectively, for published and unpublished research. Community-based studies and institutional-based studies also yield a prevalence of dropout 39.04% and 13.73% respectively. Dropout rate was 22.66% for sample sizes under 500 and 18.01% for sample sizes beyond 500. In Sub-Saharan Africa, the prevalence of vaccination dropout was high. Community education about vaccinations importance should be prioritized.
免疫接种是针对儿童发病率和死亡率的具有成本效益的预防策略。检索了 PubMed、Google Scholar、Scopus、Science Direct 和在线机构知识库。使用 Microsoft excel 提取数据。进行了 Begg 等级检验和 Egger 回归检验。进行了汇总患病率、亚组分析、敏感性分析和荟萃回归分析。本研究共纳入 12 篇文章。疫苗接种脱落的汇总患病率为 26.06%（95%CI：11.59，30.53），I2=91.2%。在亚组分析中，尼日利亚的疫苗接种脱落率最高（33.59%）。发表和未发表的研究分别为 18.01%和 29.25%。基于社区的研究和基于机构的研究的辍学率分别为 39.04%和 13.73%。样本量小于 500 的辍学率为 22.66%，样本量大于 500 的辍学率为 18.01%。在撒哈拉以南非洲，疫苗接种脱落率很高。应优先开展关于疫苗接种重要性的社区教育。
