Wnt抑制剂可降低未折叠蛋白反应并增强硼替佐米诱导的多发性骨髓瘤细胞死亡。 - Suppr

Wnt inhibitors reduce the unfolded protein response and enhance bortezomib-induced cell death in multiple myeloma.

作者信息

Spaan Ingrid, van Nieuwenhuijzen Niels, Kimman Thomas, Rockx-Brouwer Dedeke, Tieland Ralph G, Maurice Madelon M, Minnema Monique C, Raymakers Reinier A, Peperzak Victor

机构信息

Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

出版信息

Blood Adv. 2023 Apr 11;7(7):1103-1107. doi: 10.1182/bloodadvances.2022008442.

DOI:10.1182/bloodadvances.2022008442

PMID:36459495

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10111341/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abae/10111341/c2fe895934b9/BLOODA_ADV-2022-008442-gr1.jpg

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Wnt inhibitors reduce the unfolded protein response and enhance bortezomib-induced cell death in multiple myeloma.

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