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儿童神经系统疾病:运动障碍。

Childhood Neurologic Conditions: Movement Disorders.

机构信息

Mayo Clinic Rochester Department of Neurology, 200 First St SW Floor 8, Rochester, MN 55905.

出版信息

FP Essent. 2022 Dec;523:20-26.

Abstract

Most movement disorders in children are hyperkinetic. The most common type is tic disorders, which can involve motor and phonic tics and are classified as simple or complex. Motor or phonic tics that persist for more than 1 year are defined as persistent (chronic) tic disorder. Tourette syndrome can be diagnosed if a child has multiple motor tics and at least one phonic tic for more than 1 year with onset before age 18 years. Children with Tourette syndrome may have symptoms of attention-deficit/hyperactivity disorder, obsessive-compulsive disorder, depression, or behavioral disorders. Chorea can be seen as a symptom of rheumatic fever (Sydenham chorea), in children with a history of kernicterus, and in dyskinetic cerebral palsy. Chorea also may be part of an underlying metabolic or genetic condition. Dystonia is characterized by repetitive contortions and posturing of the limbs and body. It can be isolated or part of an underlying neurologic condition. Tremor can occur as a manifestation of essential tremor or can be an enhanced physiologic tremor exacerbated by drugs, illness, or stimulants. Ataxia most often is seen as a postinfectious or postvaccination acute cerebellar ataxia. Progressive ataxias are consistent with an underlying metabolic or genetic condition. Transient and developmental movement disorders include benign neonatal sleep myoclonus, jitteriness in neonates, shuddering, and stereotypies.

摘要

大多数儿童运动障碍为多动性障碍。最常见的类型是抽动障碍,可涉及运动性和发声性抽动,分为简单性或复杂性。持续时间超过 1 年的运动性或发声性抽动被定义为持续性(慢性)抽动障碍。如果儿童在 18 岁之前出现超过 1 年的多种运动性抽动和至少一种发声性抽动,则可诊断为妥瑞氏综合征。患有妥瑞氏综合征的儿童可能有注意力缺陷/多动障碍、强迫症、抑郁或行为障碍的症状。舞蹈病可作为风湿热(风湿性舞蹈病)、有核黄疸病史和舞蹈型脑瘫的症状出现。舞蹈病也可能是潜在代谢或遗传疾病的一部分。肌张力障碍的特征是四肢和身体的重复性扭曲和姿势异常。它可以是孤立的,也可以是潜在神经疾病的一部分。震颤可以是特发性震颤的表现,也可以是药物、疾病或兴奋剂加重的生理性震颤增强。共济失调最常见于感染后或疫苗接种后的急性小脑共济失调。进行性共济失调与潜在的代谢或遗传状况一致。短暂性和发育性运动障碍包括良性新生儿睡眠肌阵挛、新生儿颤抖、颤抖和刻板动作。

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