Department of Ophthalmology, Bi Shan Hospital of Chongqing, Chongqing, 402700, China.
Department of Ophthalmology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Sci Rep. 2022 Dec 5;12(1):21026. doi: 10.1038/s41598-022-25591-7.
To explore the risk factors for allergic conjunctivitis (AC) in Chinese children. We recruited 176 children who suffered from AC and a control group comprising 131 normal subjects in southern China. Each participant completed a questionnaire and underwent multiple eye examinations and a skin prick test (SPT). The data of the questionnaire, the scores of the symptoms/signs and the results of the SPT were analysed. The rate of parental allergic history in the case group was much higher than that in the control group (P < 0.01). Compared with the control group, the case group was more likely to have other concomitant diseases (P < 0.01). The scores of ocular symptoms/signs had a significant correlation with the clinical duration of AC in the case group (P < 0.01). Children with other concomitant diseases or a parental allergic history were more likely to have AC.
探索中国儿童过敏性结膜炎（AC）的危险因素。
我们招募了 176 例 AC 患儿和 131 例来自中国南方的正常对照。每位参与者都完成了一份问卷，并接受了多项眼部检查和皮肤点刺试验（SPT）。对问卷数据、症状/体征评分和 SPT 结果进行了分析。
病例组的父母过敏史发生率明显高于对照组（P<0.01）。与对照组相比，病例组更可能伴有其他伴随疾病（P<0.01）。病例组眼部症状/体征评分与 AC 的临床病程呈显著正相关（P<0.01）。
伴有其他伴随疾病或父母过敏史的儿童更容易患 AC。
