Department of Public Health, College of Life Sciences, Brigham Young University, 2063 Life Sciences Building, Provo, UT, 84602, USA.
BMC Psychiatry. 2022 Dec 5;22(1):765. doi: 10.1186/s12888-022-04335-x.
Mental health disorders can adversely affect relationships and are heritable. Yet, there is a high prevalence of mental illness in spouses and partners of those with mental illness. This study will assess within- and cross-mental health disorder correlations in husband-and-wife pairs.
A cross-sectional study design was employed using medical claims data from the Deseret Mutual Benefit Administrators (DMBA), linked to demographic information from employee eligibility files, 2020. Analyses involved 21,027 contract holders aged 18-64 (68.6% male, 31.4% female), with sub-analyses on 16,543 married individuals. Summary statistics, as well as rates, and rate ratios adjusted for age, sex, and dependent child status were calculated to describe the data.
The rate of stress is 19.2%, anxiety is 26.4%, and depression is 23.6% in spouses of contract holders with the same respective disorders. Rates of stress, anxiety, and depression in a spouse are greatest if the contract holder has schizophrenia. Rates of mental illness in wives of male contract holders experiencing mental health disorders tend to be greater than the rates of mental illness in husbands of female contract holders experiencing mental health disorders. Rates of stress, anxiety, and depression in spouses of contract holders tend to be 2-3 times greater when the contract holder has a mental health disorder, after adjusting for the contract holder's age, sex, dependent child status, and difference in age within husband-and-wife pairs. However, differences in the magnitude of observed associations vary. The rate of a spouse having stress is 5.5 times greater if the contract holder has schizophrenia (vs. does not have schizophrenia), whereas the rate of a spouse having stress is 1.4 times greater if the contract holder has sleep apnea (vs. does not have sleep apnea).
Mental health disorders in spouses of contract holders are greater if the contract holder has a mental health disorder, more so when the contract holder has more serious mental illness. Both within- and cross-mental disorder correlations exist. These results have implications on relationship quality and the mental health of offspring.
心理健康障碍会对人际关系产生不利影响，并且具有遗传性。然而，精神疾病患者的配偶和伴侣中精神疾病的发病率很高。本研究将评估夫妻双方精神障碍的内相关和交叉相关。
采用横断面研究设计，使用来自 Deseret Mutual Benefit Administrators（DMBA）的医疗索赔数据，与员工资格档案中的人口统计信息相关联，时间为 2020 年。分析涉及 21,027 名年龄在 18-64 岁之间的合同持有者（68.6%为男性，31.4%为女性），并对 16,543 对已婚个体进行了亚分析。为描述数据，计算了汇总统计数据以及按年龄、性别和受抚养子女状况调整后的发生率和调整后率比。
在患有同种精神障碍的合同持有者的配偶中，压力的发生率为 19.2%，焦虑的发生率为 26.4%，抑郁的发生率为 23.6%。如果合同持有者患有精神分裂症，则配偶的压力、焦虑和抑郁发生率最高。在患有精神健康障碍的男性合同持有者的妻子中，精神疾病的发生率往往高于患有精神健康障碍的女性合同持有者的丈夫。在调整合同持有者的年龄、性别、受抚养子女状况以及夫妻之间的年龄差异后，当合同持有者患有精神健康障碍时，配偶的压力、焦虑和抑郁发生率往往会增加 2-3 倍。然而，观察到的关联程度存在差异。如果合同持有者患有精神分裂症（而非没有精神分裂症），则配偶患有压力的发生率是 5.5 倍；如果合同持有者患有睡眠呼吸暂停（而非没有睡眠呼吸暂停），则配偶患有压力的发生率是 1.4 倍。
如果合同持有者患有精神健康障碍，则合同持有者的配偶的精神健康障碍更为严重，如果合同持有者患有更严重的精神疾病，则更为严重。存在内在和交叉精神障碍相关性。这些结果对关系质量和后代的心理健康有影响。
