Research Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Health Institute of the Balearic Islands (IDISBA), 07120 Palma de Mallorca, Spain.
Nutrients. 2022 Apr 26;14(9):1813. doi: 10.3390/nu14091813.
(1) Background: Physical inactivity has been linked to NAFLD, and exercise has been reported as useful to reduce intrahepatic fat content in NAFLD. (2) Objectives: To assess the physical activity (PA) and fitness status after a six-month lifestyle intervention (diet and PA) in adults with NAFLD and metabolic syndrome (MetS). (3) Design: Prospective cohort analysis of data obtained between baseline and six-year parallel-group randomized trial (n = 155, aged 40-60 years old, with MetS and NAFLD). Participants were randomized into three nutritional and PA intervention groups: Conventional diet (CD); MedDiet-high meal frequency (MD-HMF); MedDiet-physical activity (MD-PA). (4) Methods: PA and fitness status were assessed using a validated Minnesota questionnaire, ALPHA-FIT test battery, accelerometers, and functional fitness score. Information related to age, gender, education level, marital status, socioeconomic status, smoking habit, and alcohol consumption were also obtained. (5) Results: The CD group had higher improvement in standing handgrip than the MD-HMF group. The MD-PA group did more modified push-up repetitions than the CD group. The MD-PA and CD groups showed higher sitting handgrip than the MD-HMF group. The MD-HMF group showed the highest decrease in aerobic capacity. The MD-PA group showed lower light intensity PA/day than the CD and MD-HMF groups. The MD-PA group showed higher moderate intensity PA than the CD and MD-HMF groups. The CD group reported more METs per day than the MD-HMF group. (6) Conclusions: Lifestyle six-month intervention with diet and regular PA improved functional fitness in middle-aged patients with NAFLD and MetS. Aerobic capacity improved in patients who followed a Mediterranean diet and regular training sessions at six months.
(1) 背景：缺乏身体活动与 NAFLD 有关，有报道称运动有助于减少 NAFLD 患者的肝内脂肪含量。(2) 目的：评估患有非酒精性脂肪性肝病（NAFLD）和代谢综合征（MetS）的成年人在接受六个月生活方式干预（饮食和身体活动）后的身体活动（PA）和健康状况。(3) 设计：对基线至六年平行组随机试验（n=155，年龄 40-60 岁，患有 MetS 和 NAFLD）期间获得的数据进行前瞻性队列分析。参与者被随机分为三个营养和 PA 干预组：常规饮食（CD）；地中海饮食高餐频（MD-HMF）；地中海饮食-体力活动（MD-PA）。(4) 方法：使用经过验证的明尼苏达州问卷、ALPHA-FIT 测试电池、加速度计和功能健身评分评估 PA 和健康状况。还获得了与年龄、性别、教育水平、婚姻状况、社会经济地位、吸烟习惯和饮酒有关的信息。(5) 结果：与 MD-HMF 组相比，CD 组的站立握力改善更大。与 CD 组相比，MD-PA 组的改良俯卧撑重复次数更多。与 MD-HMF 组相比，MD-PA 和 CD 组的坐姿握力更高。MD-HMF 组的有氧能力下降最大。与 CD 和 MD-HMF 组相比，MD-PA 组的低强度体力活动/天较少。与 CD 和 MD-HMF 组相比，MD-PA 组的中等强度体力活动更多。CD 组报告的每天活动代谢当量（METs）多于 MD-HMF 组。(6) 结论：六个月的饮食和定期 PA 生活方式干预改善了患有 NAFLD 和 MetS 的中年患者的功能健康。遵循地中海饮食和定期训练的患者在六个月时有氧能力提高。
