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足月臀位单胎胎儿宫颈成熟后的新生儿发病率

Neonatal Morbidity after Cervical Ripening with a Singleton Fetus in a Breech Presentation at Term.

作者信息

Berthommier Laura, Planche Lucie, Ducarme Guillaume

机构信息

Department of Obstetrics and Gynecology, Centre Hospitalier Departemental, 85000 La Roche sur Yon, France.

Clinical Research Center, Centre Hospitalier Departemental, 85000 La Roche sur Yon, France.

出版信息

J Clin Med. 2022 Nov 30;11(23):7118. doi: 10.3390/jcm11237118.

DOI:10.3390/jcm11237118
PMID:36498693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9736943/
Abstract

Vaginal delivery in women with a breech presentation is part of common practice in France despite much debate, and the induction of labor (IOL) with a fetus in a breech presentation at term remains uncommon. Little is known about the effectiveness of cervical ripening and its neonatal and maternal safety in these women. We present a retrospective study of 362 women who gave birth to a live singleton fetus in a breech presentation at term. The objective was to compare severe maternal and neonatal morbidity according to the planned mode of labor (spontaneous labor or the induction of labor (IOL) with a favorable cervix, cervical ripening, or elective cesarean delivery) and, specifically, to compare cervical ripening to the other modes of labor. The rate of severe neonatal morbidity was 3.0% and was significantly higher after the IOL compared to elective cesarean delivery ( = 0.02), and the severe maternal morbidity rates were similar. Multivariable logistic regression analysis found no significant association between cervical ripening and either composite severe neonatal (adjusted odds ratio [aOR] 2.80, 95% confidence interval [CI] 0.10-43.6) or maternal morbidity (aOR 1.29, 95% CI 0.05-11.5). Our results support a policy of offering cervical ripening to the appropriately selected candidates with a singleton fetus in a breech presentation at term without increasing the incidence of severe maternal and neonatal morbidity.

摘要

尽管存在诸多争议,但臀位分娩在法国仍是常见的分娩方式,而足月臀位胎儿的引产(IOL)仍不常见。对于这些女性宫颈成熟的有效性及其新生儿和产妇安全性,人们知之甚少。我们对362例足月分娩单胎活产臀位胎儿的女性进行了一项回顾性研究。目的是根据计划的分娩方式(自然分娩或宫颈条件良好时的引产(IOL)、宫颈成熟或择期剖宫产)比较严重的孕产妇和新生儿发病率,特别是将宫颈成熟与其他分娩方式进行比较。严重新生儿发病率为3.0%,与择期剖宫产相比,引产(IOL)后的发病率显著更高(P = 0.02),严重孕产妇发病率相似。多变量逻辑回归分析发现,宫颈成熟与复合严重新生儿发病率(调整优势比[aOR] 2.80,95%置信区间[CI] 0.10 - 43.6)或孕产妇发病率(aOR 1.29,95% CI 0.05 - 11.5)之间均无显著关联。我们的结果支持一项政策,即向适当选择的足月单胎臀位胎儿的孕妇提供宫颈成熟,而不增加严重孕产妇和新生儿发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67b0/9736943/fe053e15bf35/jcm-11-07118-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67b0/9736943/fe053e15bf35/jcm-11-07118-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67b0/9736943/fe053e15bf35/jcm-11-07118-g001.jpg

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本文引用的文献

1
Cervical maturation in breech presentation: Mechanical versus prostaglandin methods.臀位时宫颈成熟的处理:机械方法与前列腺素方法比较。
J Gynecol Obstet Hum Reprod. 2022 Jun;51(6):102404. doi: 10.1016/j.jogoh.2022.102404. Epub 2022 May 6.
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Cervical ripening for a singleton fetus in breech prensentation at term: Comparison between mechanical and pharmaceutical methods.足月臀位单胎妊娠促宫颈成熟:机械方法与药物方法的比较。
J Gynecol Obstet Hum Reprod. 2022 Jan;51(1):102258. doi: 10.1016/j.jogoh.2021.102258. Epub 2021 Oct 22.
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Induction of labor in breech presentations - a retrospective cohort study.
臀位分娩引产——一项回顾性队列研究。
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4
Breech presentation: Clinical practice guidelines from the French College of Gynaecologists and Obstetricians (CNGOF).臀先露:法国妇产科医师学会(CNGOF)临床实践指南
Eur J Obstet Gynecol Reprod Biol. 2020 Sep;252:599-604. doi: 10.1016/j.ejogrb.2020.03.033. Epub 2020 Mar 25.
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Association between planned mode of delivery and severe maternal morbidity in women with breech presentations: A secondary analysis of the PREMODA prospective general population study.臀位产妇计划性分娩方式与严重产妇发病率的相关性:PREMODA 前瞻性一般人群研究的二次分析。
J Gynecol Obstet Hum Reprod. 2020 Feb;49(2):101662. doi: 10.1016/j.jogoh.2019.101662. Epub 2019 Dec 4.
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[Breech Presentation: CNGOF Guidelines for Clinical Practice - Labour and Induction].[臀先露:CNGOF临床实践指南 - 分娩与引产]
Gynecol Obstet Fertil Senol. 2020 Jan;48(1):136-147. doi: 10.1016/j.gofs.2019.10.022. Epub 2019 Oct 31.
7
Is induction of labor a reasonable option for breech presentation?臀位分娩时引产是否合理?
Acta Obstet Gynecol Scand. 2019 Jul;98(7):885-893. doi: 10.1111/aogs.13557. Epub 2019 Feb 24.
8
[Comparison of obstetric prognosis of attempts of breech delivery: Spontaneous labor versus induced labor].[臀位分娩尝试的产科预后比较:自然分娩与引产]
Gynecol Obstet Fertil Senol. 2018 Sep;46(9):632-638. doi: 10.1016/j.gofs.2018.07.003. Epub 2018 Aug 28.
9
Comparison of outcomes between induction of labor and spontaneous labor for term breech - A systemic review and meta analysis.足月臀位引产与自然分娩结局的比较——一项系统评价与荟萃分析
Eur J Obstet Gynecol Reprod Biol. 2018 Mar;222:155-160. doi: 10.1016/j.ejogrb.2017.12.031. Epub 2017 Dec 16.
10
Labour induction practices in France: A population-based declarative survey in 94 maternity units.法国的引产实践:一项基于94个产科单位的人口声明性调查。
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