Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, 20138 Milan, Italy.
Department of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Nutrients. 2022 Nov 29;14(23):5068. doi: 10.3390/nu14235068.
Olfactory and gustatory dysfunction are recognized as common symptoms in patients with COVID-19, with a prevalence ranging, respectively, between 41-61% and 38.2-49%. This review focused on relating the variations in dietary habits with the reduction/loss of smell and/or taste in patients who contracted the COVID-19 infection. Primarily, we reviewed the main pathological mechanisms involved in COVID 19-induced anosmia/dysosmia and ageusia/dysgeusia. Then, we explored and summarized the behavioural changes in food intake and body weight during the COVID-19 pandemic in relation to sensory impairment and the underlying mechanisms. Most studies on this topic argue that the altered chemosensory perception (taste and smell) mainly induces reduced appetite, leading to a faster fullness sensation during the consumption of a meal and, therefore, to a decrease in body weight. On the other hand, a reduced perception of the food's sensory properties may trigger compensatory responses that lead some individuals to increase food intake with a different effect on body weight. Regarding body weight, most studies evaluated malnutrition in patients hospitalized for COVID-19; more studies are warranted to investigate nutritional status specifically in non-hospitalized patients with olfactory and gustatory dysfunctions caused by COVID-19 infection.
嗅觉和味觉障碍是 COVID-19 患者常见的症状,其患病率分别在 41-61%和 38.2-49%之间。本综述主要关注 COVID-19 感染患者嗅觉/味觉减退/丧失与饮食习惯变化之间的关系。首先,我们综述了 COVID-19 引起的嗅觉障碍/味觉障碍和味觉减退/味觉障碍的主要病理机制。然后,我们探讨并总结了 COVID-19 大流行期间与感觉障碍相关的食物摄入和体重的行为变化及其潜在机制。关于这个主题的大多数研究表明,改变的化学感觉感知(味觉和嗅觉)主要导致食欲下降,导致在进食过程中更快地感到饱腹感,从而导致体重下降。另一方面,对食物感官特性的感知降低可能会引发代偿性反应,导致一些人增加食物摄入,对体重的影响也不同。关于体重,大多数研究评估了因 COVID-19 住院患者的营养不良情况;需要更多的研究来专门调查 COVID-19 感染引起的嗅觉和味觉障碍的非住院患者的营养状况。
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