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病例报告:小肠转移性乳腺癌:一例病例报告及文献综述

Case Report: Small intestinal metastatic breast cancer: A case report and literature review.

作者信息

Li Yishan, Zhang Lianru, Yu Huiping, Xin Xiaoyan, He Jian, Yao Yongzhong, Liu Baorui, Li Rutian, Xie Li

机构信息

The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

出版信息

Front Oncol. 2022 Nov 23;12:900832. doi: 10.3389/fonc.2022.900832. eCollection 2022.

DOI:10.3389/fonc.2022.900832
PMID:36505863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9732937/
Abstract

Breast cancer is considered a malignant tumor with the highest incidence among women and is prone to develop distant metastasis. Small intestinal metastasis of breast cancer, however, is relatively rare. This case report describes a 49-year-old Chinese female patient who presented with small intestinal obstruction and was diagnosed with lobular breast cancer with small intestinal and contralateral breast metastasis. Clinical manifestations, clinicopathological features and potential mechanisms of metastasis, along with diagnosis and treatment, are discussed with a review of the relevant literature. Although small intestinal metastasis is rare in breast cancer, we should keep high alert on the possibility of gastrointestinal metastasis when treating lobular breast cancer patients.

摘要

乳腺癌被认为是女性中发病率最高的恶性肿瘤,且易于发生远处转移。然而,乳腺癌小肠转移相对少见。本病例报告描述了一名49岁的中国女性患者,她因小肠梗阻就诊,被诊断为小叶型乳腺癌伴小肠及对侧乳腺转移。本文结合相关文献复习,讨论了其临床表现、临床病理特征、转移的潜在机制以及诊断和治疗。虽然小肠转移在乳腺癌中少见,但在治疗小叶型乳腺癌患者时,我们应高度警惕胃肠道转移的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/0e5f7dff87d2/fonc-12-900832-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/dbbfac6d01d7/fonc-12-900832-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/bf63e1afe8fe/fonc-12-900832-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/eeacc8ab5144/fonc-12-900832-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/0e5f7dff87d2/fonc-12-900832-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/dbbfac6d01d7/fonc-12-900832-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/bf63e1afe8fe/fonc-12-900832-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/eeacc8ab5144/fonc-12-900832-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6733/9732937/0e5f7dff87d2/fonc-12-900832-g004.jpg

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Case Report: Small intestinal metastatic breast cancer: A case report and literature review.病例报告:小肠转移性乳腺癌:一例病例报告及文献综述
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本文引用的文献

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Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.浸润性小叶乳腺癌患者的当前和未来诊断及治疗策略。
Ann Oncol. 2022 Aug;33(8):769-785. doi: 10.1016/j.annonc.2022.05.006. Epub 2022 May 21.
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Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses.乳腺癌的肿瘤间基因组异质性:原发性早期乳腺癌和复发的综合基因组特征。
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Head-to-Head Evaluation of F-FES and F-FDG PET/CT in Metastatic Invasive Lobular Breast Cancer.
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Int J Oncol. 2018 Jun;52(6):1886-1898. doi: 10.3892/ijo.2018.4356. Epub 2018 Apr 4.
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Small bowel obstruction from distant metastasis of primary breast cancer: a case report.原发性乳腺癌远处转移导致小肠梗阻:一例报告
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An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells.生长分化因子(GDF)15的自分泌/旁分泌回路在维持乳腺癌干细胞样细胞方面发挥作用。
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