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[人类免疫缺陷病毒感染通过同种异体移植的传播性]

[Transmissibility of HIV infections via allogeneic transplants].

作者信息

Wilmes E, Gürtler L, Wolf H

出版信息

Laryngol Rhinol Otol (Stuttg). 1987 Jun;66(6):332-4.

PMID:3650657
Abstract

HIV-infections can be transferred by blood and blood products, semen or organ transplants. For this reason, the WHO recommended a screening of all donors of blood, semen, tissues and organs. Those who belong to high-risk groups should be excluded from donations. If this recommendation should be also applied to cialit preserved auditory aussicles, this would probably mean the end of allogeneic transplantations of middle-ear surgery which are being performed daily. Therefore, we carried out experimental examinations with HIV-infected auditory aussicles in cialit. According to our results, it can be assumed that a virus-destruction takes place via a cialit-treatment. The same applies to solvent-dried fascia as to auditory aussicles which have been preserved in the same way. Consequently, there is no objection to further application of these allogeneic transplants in respect to HIV-infections.

摘要

艾滋病毒感染可通过血液及血液制品、精液或器官移植传播。因此,世界卫生组织建议对所有血液、精液、组织和器官捐献者进行筛查。属于高危群体的人员应被排除在捐献之外。如果这一建议也应用于甲醛保存的听小骨,这可能意味着每天都在进行的中耳手术同种异体移植的终结。因此,我们用甲醛处理过的感染艾滋病毒的听小骨进行了实验检查。根据我们的结果,可以假定通过甲醛处理会发生病毒破坏。对于以同样方式保存的溶剂干燥筋膜和听小骨也是如此。因此,就艾滋病毒感染而言,对于这些同种异体移植的进一步应用没有异议。

相似文献

1
[Transmissibility of HIV infections via allogeneic transplants].[人类免疫缺陷病毒感染通过同种异体移植的传播性]
Laryngol Rhinol Otol (Stuttg). 1987 Jun;66(6):332-4.
2
[Preservation and application possibilities of allogenic (homologous) transplants in the ear, nose and throat region].
HNO. 1983 Nov;31(11):371-80.
3
The effects of preservation methods on homologous incus transplants in cats.保存方法对猫同种砧骨移植的影响。
Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 1975 Jan-Feb;80(1):60-70.
4
[Donor selection and preservation methods for the prevention of transmission of AIDS and Creutzfeldt-Jakob disease via allogeneic transplants in ear surgery].
Ned Tijdschr Geneeskd. 1993 Aug 21;137(34):1708-11.
5
[Are cialit-preserved ossicles as middle ear implants still bacteriologically defensible? Their replacement by pre-formed implants fashioned from teeth].[作为中耳植入物的人工镫骨在细菌学上仍站得住脚吗?用牙齿制成的预制植入物替代它们]
Laryngorhinootologie. 1990 Jun;69(6):327-32. doi: 10.1055/s-2007-998202.
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[Bacteriologic studies on the preservation of bone implants].[骨植入物保存的细菌学研究]
Laryngol Rhinol Otol (Stuttg). 1985 Sep;64(9):489-91.
7
[Effect of the preservation time on the antigenic structure of allogeneic cartilage and bone preparations preserved in cialit].
Dtsch Zahnarztl Z. 1982 Oct;37(10):850-4.
8
[Comparative studies on the behavior of homeoplastic, preserved in Cialit ear ossicles after implantation in the middle ear of guinea pigs and humans].[同种异体、用西阿利特保存的听小骨植入豚鼠和人类中耳后的行为比较研究]
Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1970;196(2):130-3.
9
[Homologous transplants in the middle ear (author's transl)].中耳的同种移植(作者译)
Laryngol Rhinol Otol (Stuttg). 1975 Mar;54(3):191-5.
10
[Comparative results in graft preservation (tympanic membrane, ear ossicles) in cialit and by refrigeration using biotherapeutics].[在使用生物疗法的情况下,西阿利特(Cialit)保存与冷藏保存(鼓膜、听小骨)的比较结果]
Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1971;199(2):741-2.

引用本文的文献

1
A critical analysis of human immunodeficiency virus transmission using human cartilage allografts.使用人类同种异体软骨移植对人类免疫缺陷病毒传播进行的批判性分析。
Eur Arch Otorhinolaryngol. 1993;250(1):55-8. doi: 10.1007/BF00176950.
2
Absence of HIV-1 DNA in cartilage from HIV-positive patients.HIV阳性患者软骨中未检测到HIV-1 DNA。
Eur Arch Otorhinolaryngol. 1994;251(6):347-9. doi: 10.1007/BF00171543.