Moshref Mohammad, Modarresi Alireza, Razzaghi Negar
Retired Professor of Stomatology and Oral & Maxillofacial Pathology of Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Dept. of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, Tehran Islamic Azad University of Medical Sciences, Dental Branch, Tehran, Iran.
J Dent (Shiraz). 2022 Sep;23(3):327-335. doi: 10.30476/DENTJODS.2021.90454.1491.
Osteoblastoma is a solitary benign bone-forming neoplasm, which comprises 1% of all primary bone tumors. Multifocal benign osteoblastoma of the jaws is very rare. Osteoblastoma must be differentiated from other similar bone-forming lesions such as osteoid osteoma and osteosarcoma for correct diagnosis and proper treatment planning. Therefore, precise examination of the patient and correlation with radiographic and histological features are essential for the best treatment and prognosis. This study reports a rare case of multifocal osteoblastoma in a 30-year-old female, involving the mandible and the maxilla, which was treated by surgical excision, iliac bone graft reconstruction, and implantation. Complete surgical excision is necessary to treat osteoblastoma with a good prognosis. The patient was followed-up for four years postoperatively, and there were no signs of recurrence in the panoramic view or the clinical examination.
骨母细胞瘤是一种孤立性良性成骨性肿瘤,占所有原发性骨肿瘤的1%。颌骨多灶性良性骨母细胞瘤非常罕见。为了正确诊断和制定恰当的治疗方案,必须将骨母细胞瘤与其他类似的成骨性病变如骨样骨瘤和骨肉瘤相鉴别。因此,对患者进行精确检查并结合影像学和组织学特征对于最佳治疗和预后至关重要。本研究报告了一例罕见的30岁女性多灶性骨母细胞瘤病例,累及下颌骨和上颌骨,采用手术切除、髂骨移植重建和植入治疗。完整的手术切除对于治疗骨母细胞瘤并获得良好预后是必要的。患者术后随访四年,全景片和临床检查均未发现复发迹象。