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贝尔麻痹与二期梅毒:通过免疫荧光检测脑脊液中的螺旋体

Bell's palsy and secondary syphilis: CSF spirochetes detected by immunofluorescence.

作者信息

Davis L E, Sperry S

出版信息

Ann Neurol. 1978 Oct;4(4):378-80. doi: 10.1002/ana.410040416.

Abstract

Although Bell's palsy is usually idiopathic, occasional cases may have an identifiable infectious cause. When facial paralysis results from syphilis, it usually develops during the tertiary meningovascular stage. We report a 30-year-old man with secondary syphilis who developed facial paralysis associated with acute syphilitic meningitis. Spirochetes were identified in the cerebrospinal fluid by immunofluorescence using standard reagents from the fluorescent treponemal antibody absorption (FTA-ABS) test. Patients with Bell's palsy should be screened for syphilis with a blood FTA-ABS test, and treatment with corticosteroids should be considered only after an infectious cause has been excluded.

摘要

虽然贝尔麻痹通常是特发性的,但偶尔也可能有可识别的感染原因。当梅毒导致面瘫时,通常在三期脑膜血管梅毒阶段出现。我们报告一名30岁继发性梅毒男性患者,其出现与急性梅毒性脑膜炎相关的面瘫。通过使用荧光密螺旋体抗体吸收试验(FTA-ABS)的标准试剂进行免疫荧光检测,在脑脊液中发现了螺旋体。贝尔麻痹患者应通过血液FTA-ABS试验进行梅毒筛查,只有在排除感染原因后才应考虑使用皮质类固醇进行治疗。

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