谷胱甘肽与姜黄素在系统性红斑狼疮治疗中的关键作用比较：一项系统评价
The Key Role of Glutathione Compared to Curcumin in the Management of Systemic Lupus Erythematosus: A Systematic Review.
作者信息
Ravi Niriksha, Choday Silpa, Shantha Kumar Vivig, Kc Anil, Parisapogu Anusha, Ojinna Blessing T, Tran Hadrian Hoang-Vu, Sherpa Mingma L, Shrestha Nilasma, Mohammed Lubna
机构信息
Internal Medicine and Neurology, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
出版信息
Cureus. 2022 Nov 10;14(11):e31324. doi: 10.7759/cureus.31324. eCollection 2022 Nov.
In recent years, many documented cases of systemic lupus erythematosus (SLE) have been on the rise. The complicated pathophysiology of the disease makes it challenging to manage. Two databases, PubMed and Google Scholar, have a detailed screening using keywords and Medical Subject Heading (MeSH) combinations. The words are "Systemic Lupus Erythematosus OR SLE OR Lupus," "Glutathione," and "Curcumin." Articles had a detailed process of screening and quality appraisal. Using the English language as a primary filtering parameter, papers over the last 20 years, dating from 2002 to 2022, are the basis of this review. We reviewed all possible human studies documenting the use of curcumin and glutathione for treating SLE. A total of 15 articles are part of this systematic review. Curcumin and glutathione can act as potent drugs for treating lupus. Curcumin can be a more promising alternative since it operates on various pathways and is a more easily accessible source.
近年来，许多系统性红斑狼疮（SLE）的记录病例呈上升趋势。该疾病复杂的病理生理学使其管理具有挑战性。两个数据库，即PubMed和谷歌学术，使用关键词和医学主题词（MeSH）组合进行了详细筛选。这些词是“系统性红斑狼疮或SLE或狼疮”、“谷胱甘肽”和“姜黄素”。文章有详细的筛选和质量评估过程。以英语作为主要筛选参数，过去20年（从2002年到2022年）的论文是本综述的基础。我们回顾了所有记录姜黄素和谷胱甘肽用于治疗SLE的可能的人体研究。本系统综述共有15篇文章。姜黄素和谷胱甘肽可作为治疗狼疮的有效药物。姜黄素可能是更有前景的选择，因为它作用于多种途径，且来源更容易获取。
Zotero 插件