Constantin Maria-Magdalena, Nita Iuliana Elena, Olteanu Rodica, Constantin Traian, Bucur Stefana, Matei Clara, Raducan Anca
University of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania.
The Second Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Exp Ther Med. 2019 Feb;17(2):1085-1090. doi: 10.3892/etm.2018.6986. Epub 2018 Nov 16.
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology, although its mechanisms involve genetic, epigenetic and environmental risk factors. Considering that SLE pathogenesis is yet to be explored, recent studies aimed to investigate the impact of diet, in terms of triggering or altering the course of the disease. To study the impact of diet on SLE pathogenesis, we conducted a search on Pubmed using the keywords 'diet and autoimmune diseases', 'diet and lupus', 'caloric restriction and lupus', 'polyunsaturated fatty acids and lupus', 'vitamin D and lupus', 'vitamin C and lupus' 'vitamin E and lupus' 'vitamin A and lupus' 'vitamin B and lupus', 'polyphenols and lupus', 'isoflavones and lupus', 'minerals and lupus', 'aminoacids and lupus', 'curcumin and lupus' and found 10,215 papers, from which we selected 47 relevant articles. The paper clearly emphasizes the beneficial role of personalized diet in patients with SLE, and the information presented could be used in daily practice. Proper diet in SLE can help preserve the body's homeostasis, increase the period of remission, prevent adverse effects of medication and improve the patient's physical and mental well-being.
系统性红斑狼疮（SLE）是一种病因不明的自身免疫性疾病，尽管其发病机制涉及遗传、表观遗传和环境风险因素。鉴于SLE的发病机制尚待探索，最近的研究旨在调查饮食在引发或改变疾病进程方面的影响。为了研究饮食对SLE发病机制的影响，我们在PubMed上使用关键词“饮食与自身免疫性疾病”、“饮食与狼疮”、“热量限制与狼疮”、“多不饱和脂肪酸与狼疮”、“维生素D与狼疮”、“维生素C与狼疮”、“维生素E与狼疮”、“维生素A与狼疮”、“维生素B与狼疮”、“多酚与狼疮”、“异黄酮与狼疮”、“矿物质与狼疮”、“氨基酸与狼疮”、“姜黄素与狼疮”进行搜索，共找到10215篇论文，从中我们筛选出47篇相关文章。该论文明确强调了个性化饮食对SLE患者的有益作用，所呈现的信息可应用于日常实践。SLE患者的合理饮食有助于维持身体的稳态，延长缓解期，预防药物不良反应，并改善患者的身心健康。
