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Elevated Childhood Insulin-related Asthma Is a Risk Factor for Reduced Lung Function.

作者信息

Carr Tara F, Stern Debra A, Morgan Wayne, Guerra Stefano, Martinez Fernando D

机构信息

University of Arizona, Tucson, Arizona.

出版信息

Am J Respir Crit Care Med. 2023 Mar 15;207(6):790-792. doi: 10.1164/rccm.202209-1654LE.

DOI:10.1164/rccm.202209-1654LE
PMID:36521027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10037476/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd0/10037476/f0be146f5a7d/rccm.202209-1654LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd0/10037476/f0be146f5a7d/rccm.202209-1654LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd0/10037476/f0be146f5a7d/rccm.202209-1654LEf1.jpg

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本文引用的文献

1
The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.胰岛素抵抗对哮喘肺功能丧失和治疗反应的影响。
Am J Respir Crit Care Med. 2022 Nov 1;206(9):1096-1106. doi: 10.1164/rccm.202112-2745OC.
2
High Insulin in Early Childhood Is Associated with Subsequent Asthma Risk Independent of Body Mass Index.儿童早期高胰岛素水平与后续哮喘风险有关，与体重指数无关。
J Allergy Clin Immunol Pract. 2022 Mar;10(3):785-792.e5. doi: 10.1016/j.jaip.2021.09.047. Epub 2021 Oct 14.
3
Insulin acutely increases agonist-induced airway smooth muscle contraction in humans and rats.
肥胖过敏母亲的后代中过敏炎症增加和肺胰岛素敏感性降低。
J Leukoc Biol. 2024 Nov 4;116(5):985-994. doi: 10.1093/jleuko/qiae135.
4
Higher levels of insulin-like growth factor-1 in cord blood associate with risk of asthma at age 3.脐带血中胰岛素样生长因子-1 水平较高与 3 岁时哮喘发病风险相关。
Pediatr Pulmonol. 2024 Feb;59(2):482-487. doi: 10.1002/ppul.26780. Epub 2023 Nov 28.
5
Maternal high-fat diet increases airway sensory innervation and reflex bronchoconstriction in adult offspring.母体高脂肪饮食增加成年后代气道感觉神经支配和反射性支气管收缩。
Am J Physiol Lung Cell Mol Physiol. 2023 Jul 1;325(1):L66-L73. doi: 10.1152/ajplung.00115.2023. Epub 2023 Jun 6.
胰岛素可显著增强人类和大鼠气道平滑肌在激动剂刺激下的收缩反应。
Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L545-L556. doi: 10.1152/ajplung.00232.2020. Epub 2021 Jan 27.
4
Insulin Modulates Cytokine Release, Collagen and Mucus Secretion in Lung Remodeling of Allergic Diabetic Mice.胰岛素调节变应性糖尿病小鼠肺重塑过程中的细胞因子释放、胶原蛋白和黏液分泌。
Front Immunol. 2017 Jun 9;8:633. doi: 10.3389/fimmu.2017.00633. eCollection 2017.
5
Obesity and Airway Dysanapsis in Children with and without Asthma.有和没有哮喘的儿童的肥胖与气道发育异常
Am J Respir Crit Care Med. 2017 Feb 1;195(3):314-323. doi: 10.1164/rccm.201605-1039OC.
6
Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma.美国有哮喘和无哮喘青少年的胰岛素抵抗、代谢综合征与肺功能
J Allergy Clin Immunol. 2015 Aug;136(2):304-11.e8. doi: 10.1016/j.jaci.2015.01.010. Epub 2015 Mar 3.
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Diabetol Metab Syndr. 2011 Sep 7;3(1):23. doi: 10.1186/1758-5996-3-23.
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Tucson Children's Respiratory Study: 1980 to present.图森儿童呼吸研究：1980年至今。
J Allergy Clin Immunol. 2003 Apr;111(4):661-75; quiz 676. doi: 10.1067/mai.2003.162.