Hibaoui Lahbib, Massik Abdelhamid, Lebbar Zina, Yahyaoui Ghita, Mahmoud Mustapha, Bougnouch Laila, Hamass Naoual, Chbani Laila, Bennani Bahia, Berrahou Mohamed Amine, Idriss Mounia Lakhdar, Hida Moustapha
Biomedical and Translational Research Laboratory, Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Microbiology and Molecular Biology Laboratory, Microorganisms Team, Genomics and Oncogene Factors, Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
Iran J Microbiol. 2022 Oct;14(5):669-676. doi: 10.18502/ijm.v14i5.10960.
Infesting nearly 50% of the world's population, are thought to cause peptic ulcers, as well as gastric adenocarcinoma. Several diagnostic methods are available to detect this bacterium; however, at least two must be used together for an accurate diagnosis. This study evaluated the use of rapid urease test for diagnosis of infection in a pediatric population.
Five gastric biopsies were taken from children during a 2-year period for the purpose of histological, molecular, bacteriological culture, and rapid urease testing.
Among 83 children, 38 were male, and 45 were female with an age ranging of 2 to 15 years. The infected group represented 31%. The rapid urease test had a sensitivity of 88.5%, a negative predictive value of 94%, a specificity of 84.2%, and a positive predictive value of 72%.
A rapid urease test may be appropriate for ruling out infection after a negative result. The positive results however, may be confirmed by a second invasive test.
这种细菌感染了近50%的世界人口，被认为会导致消化性溃疡以及胃腺癌。有几种诊断方法可用于检测这种细菌；然而，为了准确诊断，至少必须同时使用两种方法。本研究评估了快速尿素酶试验在儿科人群中诊断[细菌名称未给出]感染的应用。
在两年期间从儿童身上采集了五份胃活检组织，用于组织学、分子学、细菌培养和快速尿素酶检测。
83名儿童中，38名男性，45名女性，年龄在2至15岁之间。感染组占31%。快速尿素酶试验的敏感性为88.5%，阴性预测值为94%，特异性为84.2%，阳性预测值为72%。
快速尿素酶试验结果为阴性时，可能适合排除[细菌名称未给出]感染。然而，阳性结果可能需要通过第二次侵入性检测来确认。
