Maurer B, Flügel R M
German Cancer Research Center, Institute of Virus Research, Heidelberg, FRG.
FEBS Lett. 1987 Oct 5;222(2):286-8. doi: 10.1016/0014-5793(87)80387-3.
The primary amino acid sequence within a domain of 89 residues of the central part of the 3'-orf protein (p27 3'-orf) of human immunodeficiency virus (HIV-2) shares homology with the middle and carboxy-terminal portion of the bel3 gene product of human spumaretrovirus (HSRV). In addition, a limited region of the tat protein of HIV-2 but not HIV-1 shows a 28% degree of homology to the deduced protein sequence of the bel1 gene product of HSRV. Comparison between the viral sequences suggests that the 3'-orf and bel1 gene product of HSRV could serve similar functions to those in HIV-2.
人类免疫缺陷病毒（HIV - 2）的3'-orf蛋白（p27 3'-orf）中央部分89个残基的结构域内的一级氨基酸序列，与人泡沫逆转录病毒（HSRV）的bel3基因产物的中部和羧基末端部分具有同源性。此外，HIV - 2而非HIV - 1的tat蛋白的一个有限区域，与HSRV的bel1基因产物的推导蛋白序列显示出28%的同源性。病毒序列之间的比较表明，HSRV的3'-orf和bel1基因产物可能具有与HIV - 2中类似的功能。
