Department of Radiology, Human Medical Imaging & Intervention Center, Seoul, Korea.
Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-Ro, Dongjak-Gu, Seoul, Republic of Korea.
Sci Rep. 2022 Dec 19;12(1):21930. doi: 10.1038/s41598-022-25725-x.
We aimed to evaluate the agreement in the diagnosis of intracranial lesions between conventional pre-contrast 3D T1 magnetization-prepared rapid gradient echo (MPRAGE) and wave-CAIPI (wave-controlled aliasing in parallel imaging) MPRAGE. Institutional review board approval was obtained and informed consent was waived for this retrospective study. We included 149 consecutive patients who had undergone brain MR with both conventional MPRAGE (scan time: 5 min 42 s) and wave-CAIPI MPRAGE (scan time: 2 min 44 s) from February to June 2018. All images were independently reviewed by two radiologists for the diagnosis of intracranial lesion and scored image quality using visual analysis. One technician measured signal-to-noise ratio. The agreement for diagnosis of intracranial lesion was calculated, and the intra- and interobserver agreements were analyzed by using kappa value. For the diagnosis of intracranial lesion, the conventional and wave-CAIPI MPRAGE demonstrated 99.7% of agreement (297 of 298) in the pooled analysis with very good agreement (k = 0.994). Intra- and inter-observer agreement showed very good (k > 0.9 in all) and good (k > 0.75) agreement, respectively. In the quantitative analysis, the signal-to-noise ratio had no difference (P > 0.05 for all). The overall image quality was poorer in images of wave-CAIPI MPRAGE (P < 0.001), but motion artifact had no difference between two sequences (P = 0.06). Compared to conventional MPRAGE, pre-contrast 3D T1 wave-CAIPI MPRAGE achieved higher agreement for the diagnosis of intracranial lesions and reduced the scan time by approximately 50%.
我们旨在评估常规对比前 3D T1 磁化准备快速梯度回波（MPRAGE）和波控并行成像（CAIPI）MPRAGE 对颅内病变诊断的一致性。本回顾性研究获得了机构审查委员会的批准，并豁免了知情同意。我们纳入了 2018 年 2 月至 6 月期间 149 例连续行脑 MRI 检查的患者，均行常规 MPRAGE（扫描时间：5 分 42 秒）和波控 CAIPI MPRAGE（扫描时间：2 分 44 秒）。两位放射科医生独立对所有图像进行颅内病变诊断，并采用视觉分析对图像质量进行评分。一名技师测量信噪比。计算颅内病变诊断的一致性，并采用 Kappa 值分析观察者内和观察者间的一致性。在颅内病变的诊断中，常规和波控 CAIPI MPRAGE 在汇总分析中具有 99.7%的一致性（297/298），具有极好的一致性（k=0.994）。观察者内和观察者间的一致性均表现出极好（所有 k 值均>0.9）和良好（所有 k 值均>0.75）的一致性。在定量分析中，信噪比无差异（所有 P>0.05）。波控 CAIPI MPRAGE 的图像整体质量较差（P<0.001），但两种序列的运动伪影无差异（P=0.06）。与常规 MPRAGE 相比，对比前 3D T1 波控 CAIPI MPRAGE 对颅内病变的诊断具有更高的一致性，并将扫描时间缩短了约 50%。
