Borelli I, Olivetti E, Cappello N, Rendine S, Curtoni E S
Istituto di Genetica Medica, Università di Torino, Italy.
Hum Hered. 1987;37(4):217-21. doi: 10.1159/000153706.
A sample of healthy unrelated individuals was typed for properdin factor B (Bf) polymorphism in four Sardinian villages. Two villages, Desulo and Tonara, are located in the highlands; the other two, Orosei and Galtellì, are located in the lowlands. No heterogeneity was found between the highland and the lowland villages, whereas a significant difference was found between the Sardinian villages and continental Italy. The allele Bf-F1 shows the highest gene frequency so far observed. Typically Sardinian is the gametic association (haplotype) HLA-A30, Cw5, B18, BfF1, DR3.
对撒丁岛四个村庄中健康无血缘关系的个体样本进行了备解素因子B（Bf）多态性分型。其中两个村庄，德苏洛和托纳拉，位于高地；另外两个村庄，奥罗塞伊和加泰利，位于低地。高地村庄和低地村庄之间未发现异质性，而撒丁岛村庄与意大利大陆之间存在显著差异。等位基因Bf-F1显示出迄今观察到的最高基因频率。典型的撒丁岛配子关联（单倍型）是HLA-A30、Cw5、B18、BfF1、DR3。
