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Comparative anti-fertility effects of gossypol enantiomers in male hamsters.

作者信息

Lindberg M C, Naqvi R H, Matlin S A, Zhou R H, Bialy G, Blye R P

机构信息

EG&G Mason Research Institute, Worcester.

出版信息

Int J Androl. 1987 Aug;10(4):619-23. doi: 10.1111/j.1365-2605.1987.tb00361.x.

Abstract

The enantiomers of gossypol have been tested as male oral anti-fertility agents in hamsters. As determined by fertility tests the (-) isomer was fully active at half the effective dose of the racemate, whereas the (+) isomer exerted no anti-fertility effect.

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