Cecchini Arthur, Qureshi Mohammad H, Peshin Supriya, Othman Ahmad, Gajjar Bhavesh
Internal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Cureus. 2022 Nov 16;14(11):e31578. doi: 10.7759/cureus.31578. eCollection 2022 Nov.
Type A aortic dissection (AD) is a devastating cardiovascular emergency requiring emergent surgical intervention. Most patients with AD have several risk factors for the disease including longstanding hypertension, smoking history, atherosclerosis, and old age. Younger patients may also present with AD if a genetic disorder affecting the integrity of the aorta is present. This case presents an otherwise healthy 36-year-old male with no known significant family history who presented with an atypical presentation of aortic dissection. He described a five-day history of chest pressure made worse with exertion followed by progressive dyspnea which prompted him to seek medical attention. His initial laboratory workup revealed an elevated troponin I level which prompted a cardiology consultation in the emergency department. Transthoracic echocardiography revealed dilatation of the aortic root and aortic regurgitation. CT angiography of the chest was performed revealing a type A dissection beginning at the aortic root and terminating proximal to the right brachiocephalic artery. Involvement of the coronary arteries was suspected due to the elevated troponin I. He was taken to the operating room and underwent aortic grafting, right coronary artery bypass, and repair of the left main artery. Unfortunately, at the end of the operation, the patient went into refractory ventricular fibrillation, which progressed to asystole. He was unable to be revived.
A型主动脉夹层(AD)是一种严重的心血管急症,需要紧急手术干预。大多数AD患者有多种该病的危险因素,包括长期高血压、吸烟史、动脉粥样硬化和老年。如果存在影响主动脉完整性的遗传疾病,年轻患者也可能患AD。本病例为一名36岁的健康男性,无明显家族病史,出现了非典型的主动脉夹层表现。他描述有五天的胸部压迫感,劳累后加重,随后逐渐出现呼吸困难,促使他寻求医疗帮助。他最初的实验室检查显示肌钙蛋白I水平升高,这促使急诊科进行心脏科会诊。经胸超声心动图显示主动脉根部扩张和主动脉瓣反流。进行了胸部CT血管造影,显示A型夹层始于主动脉根部,止于右头臂动脉近端。由于肌钙蛋白I升高,怀疑冠状动脉受累。他被送往手术室,接受了主动脉移植、右冠状动脉搭桥和左主干动脉修复。不幸的是,手术结束时,患者出现难治性室颤,并进展为心搏停止。他未能复苏。