Zheng Ziyu, Ye Zi, Huang Yingxiong, Xu Jia, Cai Ruibin, Zhan Hong
Department of Emergency Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China.
J Cardiovasc Dis Res. 2013 Dec;4(4):251-3. doi: 10.1016/j.jcdr.2013.12.002. Epub 2014 Feb 7.
Acute myocardial infarction (AMI) concomitant with aortic dissection (AD) is rare but a devastating situation if misdiagnosed as simply AMI, followed by anticoagulant or thrombolytic therapy. In such cases, Standford type B AD was extremely infrequent.
To present a case with apparent concordance with the patient's history, symptoms, cardiac enzymes that lead to diagnostic error.
An 85-year-old man with chronic hypertension and coronary atherosclerotic heart disease presented in our emergency department with squeezing retrosternal chest pain and dyspnea. Elevated cardiac enzymes and electrocardiography result suggested acute non-ST-segment elevation myocardial infarction. Emergency coronary angiography demonstrated a 50-90% diffuse stenosis of the proximal and mid right coronary artery also confirmed the diagnosis. Stents were deployed thereafter. However, the patient was found to be concomitant with Standford type B AD by computed tomography angiography due to unrelieved chest pain and new onset of abdominal pain after the operation. The patient refused to have endovascular operation and died of hemorrhagic shock one week later.
AD may cause AMI due to some indirect mechanisms, and it is of utmost importance to search for the existence of AD before reperfusion therapy in AMI patients. Aortic dissection detection risk score, transthoracic echocardiography and D-dimer help early identification of AD.
急性心肌梗死(AMI)合并主动脉夹层(AD)较为罕见,但如果误诊为单纯的AMI并随后进行抗凝或溶栓治疗,情况将极为严重。在这类病例中,斯坦福B型AD极为少见。
呈现一例在病史、症状、心肌酶方面与患者情况明显相符但却导致诊断错误的病例。
一名85岁患有慢性高血压和冠状动脉粥样硬化性心脏病的男性患者因胸骨后压榨性胸痛和呼吸困难就诊于我院急诊科。心肌酶升高及心电图结果提示急性非ST段抬高型心肌梗死。急诊冠状动脉造影显示右冠状动脉近端和中段弥漫性狭窄50% - 90%,这也证实了诊断。随后置入了支架。然而,术后患者因胸痛未缓解且出现新发腹痛,经计算机断层扫描血管造影发现合并斯坦福B型AD。患者拒绝接受血管内手术,一周后死于失血性休克。
AD可能通过一些间接机制导致AMI,对于AMI患者在进行再灌注治疗前排查AD的存在至关重要。主动脉夹层检测风险评分、经胸超声心动图和D - 二聚体有助于早期识别AD。