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用于功能性电刺激的超声兼容电极

Ultrasound-Compatible Electrode for Functional Electrical Stimulation.

作者信息

Moon Sunho, Xue Xiangming, Ganesh Vidisha, Shukla Darpan, Kreager Benjamin C, Cai Qianqian, Wu Huaiyu, Zhu Yong, Sharma Nitin, Jiang Xiaoning

机构信息

The Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27606, USA.

The Joint Department of Biomedical Engineering, North Carolina State University, Raleigh, NC 27695, USA.

出版信息

Biomedicines. 2024 Aug 2;12(8):1741. doi: 10.3390/biomedicines12081741.

Abstract

Functional electrical stimulation (FES) is a vital method in neurorehabilitation used to reanimate paralyzed muscles, enhance the size and strength of atrophied muscles, and reduce spasticity. FES often leads to increased muscle fatigue, necessitating careful monitoring of the patient's response. Ultrasound (US) imaging has been utilized to provide valuable insights into FES-induced fatigue by assessing changes in muscle thickness, stiffness, and strain. Current commercial FES electrodes lack sufficient US transparency, hindering the observation of muscle activity beneath the skin where the electrodes are placed. US-compatible electrodes are essential for accurate imaging and optimal FES performance, especially given the spatial constraints of conventional US probes and the need to monitor muscle areas directly beneath the electrodes. This study introduces specially designed body-conforming US-compatible FES (US-FES) electrodes constructed with a silver nanowire/polydimethylsiloxane (AgNW/PDMS) composite. We compared the performance of our body-conforming US-FES electrode with a commercial hydrogel electrode. The findings revealed that our US-FES electrode exhibited comparable conductivity and performance to the commercial one. Furthermore, US compatibility was investigated through phantom and in vivo tests, showing significant compatibility even during FES, unlike the commercial electrode. The results indicated that US-FES electrodes hold significant promise for the real-time monitoring of muscle activity during FES in clinical rehabilitative applications.

摘要

功能性电刺激(FES)是神经康复中的一种重要方法,用于使瘫痪肌肉恢复活动、增加萎缩肌肉的尺寸和力量以及减轻痉挛。FES常常会导致肌肉疲劳加剧,因此需要仔细监测患者的反应。超声(US)成像已被用于通过评估肌肉厚度、硬度和应变的变化,为FES引起的疲劳提供有价值的见解。目前的商用FES电极缺乏足够的超声透明度,阻碍了对放置电极部位皮肤下方肌肉活动的观察。兼容超声的电极对于准确成像和优化FES性能至关重要,特别是考虑到传统超声探头的空间限制以及直接监测电极下方肌肉区域的需求。本研究介绍了一种特别设计的贴合身体的兼容超声的FES(US-FES)电极,它由银纳米线/聚二甲基硅氧烷(AgNW/PDMS)复合材料制成。我们将贴合身体的US-FES电极的性能与商用凝胶电极进行了比较。研究结果表明,我们的US-FES电极表现出与商用电极相当的导电性和性能。此外,通过体模和体内测试对超声兼容性进行了研究,结果显示与商用电极不同,即使在FES期间也具有显著的兼容性。结果表明,US-FES电极在临床康复应用中对FES期间肌肉活动的实时监测具有重大前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3ef/11352097/2b206463b59d/biomedicines-12-01741-g001.jpg

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